N₂-[(3,5-difluorophenyl)acethyl]-N₁-[(6R,7R)-5-oxo-7-phenyl-1,4-thiazepan-6-yl]-L-valinamide

Base Information

• Chemical Name: N₂-[(3,5-difluorophenyl)acethyl]-N₁-[(6R,7R)-5-oxo-7-phenyl-1,4-thiazepan-6-yl]-L-valinamide
• CAS No.: 680229-46-3
• Molecular Formula: C₂₄H₂₇F₂N₃O₃S
• Molecular Weight: 475.559

Synonyms:N₂-[(3,5-difluorophenyl)acethyl]-N₁-[(6R,7R)-5-oxo-7-phenyl-1,4-thiazepan-6-yl]-L-valinamide

Chemical Property of N₂-[(3,5-difluorophenyl)acethyl]-N₁-[(6R,7R)-5-oxo-7-phenyl-1,4-thiazepan-6-yl]-L-valinamide

Chemical Property:

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Technology Process of N₂-[(3,5-difluorophenyl)acethyl]-N₁-[(6R,7R)-5-oxo-7-phenyl-1,4-thiazepan-6-yl]-L-valinamide

There total 1 articles about N₂-[(3,5-difluorophenyl)acethyl]-N₁-[(6R,7R)-5-oxo-7-phenyl-1,4-thiazepan-6-yl]-L-valinamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N1-[(6,7-cis)-5-oxo-7-phenyl-1,4-thiazepan-6-yl]-L-valinamide (680231-28-1) + 3,5-difluorophenyl acetic acid (105184-38-1) → N2-[(3,5-difluorophenyl)acethyl]-N1-[(6R,7R)-5-oxo-7-phenyl-1,4-thiazepan-6-yl]-L-valinamide (680229-46-3) + C24H27F2N3O3S

Guidance literature:

With 4-methyl-morpholine; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 20 ℃;

upstream raw materials:

N₁-[(6,7-cis)-5-oxo-7-phenyl-1,4-thiazepan-6-yl]-L-valinamide

3,5-difluorophenyl acetic acid

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