O-(1,1-dimethylethyl)-N-{[(9H-fluoren-9-ylmethyl)oxy]carbonyl}-N-[(2-methylimidazo[2,1-b][1,3]thiazol-6-yl)methyl]-L-tyrosinamide

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Chemical Name:O-(1,1-dimethylethyl)-N-{[(9H-fluoren-9-ylmethyl)oxy]carbonyl}-N-[(2-methylimidazo[2,1-b][1,3]thiazol-6-yl)methyl]-L-tyrosinamide
CAS No.:891845-30-0
Molecular Formula:C₃₅H₃₆N₄O₄S
Molecular Weight:608.761
Hs Code.:

Synonyms:O-(1,1-dimethylethyl)-N-{[(9H-fluoren-9-ylmethyl)oxy]carbonyl}-N-[(2-methylimidazo[2,1-b][1,3]thiazol-6-yl)methyl]-L-tyrosinamide

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Chemical Property of O-(1,1-dimethylethyl)-N-{[(9H-fluoren-9-ylmethyl)oxy]carbonyl}-N-[(2-methylimidazo[2,1-b][1,3]thiazol-6-yl)methyl]-L-tyrosinamide

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Technology Process of O-(1,1-dimethylethyl)-N-{[(9H-fluoren-9-ylmethyl)oxy]carbonyl}-N-[(2-methylimidazo[2,1-b][1,3]thiazol-6-yl)methyl]-L-tyrosinamide

There total 1 articles about O-(1,1-dimethylethyl)-N-{[(9H-fluoren-9-ylmethyl)oxy]carbonyl}-N-[(2-methylimidazo[2,1-b][1,3]thiazol-6-yl)methyl]-L-tyrosinamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 71989-38-3,118488-18-9,204384-67-8
Fmoc-Tyr(tBu)-OH

: 518064-25-0
1-(2-methylimidazo[2,1-b][1,3]thiazol-6-yl)methanamine

: 891845-30-0
O-(1,1-dimethylethyl)-N-{[(9H-fluoren-9-ylmethyl)oxy]carbonyl}-N-[(2-methylimidazo[2,1-b][1,3]thiazol-6-yl)methyl]-L-tyrosinamide

Guidance literature:: With N-ethyl-N,N-diisopropylamine; HATU; In N,N-dimethyl-formamide; at 20 ℃; for 3h; Inert atmosphere;
DOI:10.1021/jm800634k