5-PHENYL-2-THIOPHENECARBALDEHYDE

Base Information

• Chemical Name: 5-PHENYL-2-THIOPHENECARBALDEHYDE
• CAS No.: 19163-21-4
• Molecular Formula: C11H8OS
• Molecular Weight: 188.25
• Hs Code.: 2934999090
• Mol file: 19163-21-4.mol

Synonyms:2-Formyl-5-phenylthiophene;2-Phenyl-5-thiophenecarboxaldehyde;5-Formyl-2-phenylthiophene;5-Phenyl-2-thiophenecarboxaldehyde;5-Phenylthiophene-2-aldehyde;5-Phenylthiophene-2-carbaldehyde;

Chemical Property of 5-PHENYL-2-THIOPHENECARBALDEHYDE

Chemical Property:

• Vapor Pressure: 8.84E-05mmHg at 25°C
• Melting Point: 92-95 °C
• Refractive Index: 1.637
• Boiling Point: 340 °C at 760 mmHg
• Flash Point: 127 °C
• PSA: 45.31000
• Density: 1.207 g/cm³
• LogP: 3.22760
• Storage Temp.: 2-8°C

Purity/Quality:

99.0% ^*data from raw suppliers

5-Phenyl-thiophene-2-carbaldehyde 95%+ ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Technology Process of 5-PHENYL-2-THIOPHENECARBALDEHYDE

There total 35 articles about 5-PHENYL-2-THIOPHENECARBALDEHYDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

5-bromo-2-thiophencarboxaldehyde (4701-17-1) + phenylboronic acid (98-80-6) → 5-phenylthiophene-2-carboxaldehyde (19163-21-4)

Guidance literature:

With potassium phosphate; (dppf)Ni(o-tol)Cl; In 1,4-dioxane; at 80 ℃; for 4h; Reagent/catalyst; Solvent; Catalytic behavior; Sealed tube;

DOI:10.1039/c9ob00561g

Reference yield: 93.0%

5-Chloro-2-thiophenecarboxaldehyde (7283-96-7) + phenylboronic acid (98-80-6) → 5-phenylthiophene-2-carboxaldehyde (19163-21-4)

Guidance literature:

With potassium carbonate; In ethanol; water; at 50 ℃; for 4h; Inert atmosphere;

DOI:10.1002/adsc.200900495

Reference yield: 92.0%

5-Chloro-2-thiophenecarboxaldehyde (7283-96-7) + triethoxyphenylsilane (780-69-8) → 5-phenylthiophene-2-carboxaldehyde (19163-21-4)

Guidance literature:

With Pd((CH₃)2C₆H₃NC(CH₃)CHC(CH₃)NC₆H₃(CH₃)2)(CH₃)(P(CH₂CH₃)3); tetrabutylammomium bromide; sodium hydroxide; In water; at 60 ℃; for 8h; Inert atmosphere;

DOI:10.1039/c0cc03535a

upstream raw materials:

2-phenylthiophene

N-methyl-N-phenylformamide

thiophene-2-carbaldehyde

benzene

Downstream raw materials:

5-phenyl-thiophene-2-carbaldehyde-semicarbazone

2-methyl-5-phenylthiophene

(4-phenyl-thiazol-2-yl)-(5-phenyl-thiophen-2-ylmethylene)-amine

5-Phenyl-2-{4-[(E)-2-(5-phenyl-thiophen-2-yl)-vinyl]-phenyl}-oxazole