C₃₁H₄₆F₃N₉O₇S

Base Information

• Chemical Name: C₃₁H₄₆F₃N₉O₇S
• CAS No.: 943601-31-8
• Molecular Formula: C₃₁H₄₆F₃N₉O₇S
• Molecular Weight: 745.824
• Mol file: 943601-31-8.mol

Synonyms:C₃₁H₄₆F₃N₉O₇S

Chemical Property of C₃₁H₄₆F₃N₉O₇S

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of C₃₁H₄₆F₃N₉O₇S

There total 18 articles about C₃₁H₄₆F₃N₉O₇S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%

C37H49F3N10O11S2 (943601-30-7) → C31H46F3N9O7S (943601-31-8)

Guidance literature:

With caesium carbonate; thiophenol; In acetonitrile; at 50 ℃; for 0.5h;

DOI:10.1021/ol070376i

Reference yield:

N-(2-[2-{2-hydroxyethoxy}ethoxy]ethyl)-2-nitro-benzenesulfonamide (943601-23-8) → C31H46F3N9O7S (943601-31-8)

Guidance literature:

Multi-step reaction with 7 steps

1.1: triethylamine / CH₂Cl₂ / 0.17 h / 20 °C

2.1: 3.15 g / sodium azide; tetra-n-butylammonium iodide / dimethylformamide / 1 h / 80 °C

3.1: triphenylphosphine / tetrahydrofuran; H₂O / 1 h / 20 °C

3.2: 53 percent / sodium carbonate / tetrahydrofuran; H₂O / 1 h / 20 °C

4.1: 980 mg / triphenylphosphine; diethyl azodicarboxylate / tetrahydrofuran; toluene / 0.17 h / 20 °C

5.1: trifluoroacetic acid / CH₂Cl₂ / 1 h / 0 °C

6.1: 1.09 g / triethylamine / dimethylformamide / 2 h / 20 °C

7.1: 52 percent / cesium carbonate; benzenethiol / acetonitrile / 0.5 h / 50 °C

With sodium azide; tetra-(n-butyl)ammonium iodide; caesium carbonate; thiophenol; triethylamine; triphenylphosphine; trifluoroacetic acid; diethylazodicarboxylate; In tetrahydrofuran; dichloromethane; water; N,N-dimethyl-formamide; toluene; acetonitrile; 4.1: Mitsunobu reaction;

DOI:10.1021/ol070376i

Reference yield:

C18H32O7SiSN2 (943601-22-7) → C31H46F3N9O7S (943601-31-8)

Guidance literature:

Multi-step reaction with 8 steps

1.1: 69 percent / tetra-n-butylammonium fluoride / tetrahydrofuran / 1 h / 20 °C

2.1: triethylamine / CH₂Cl₂ / 0.17 h / 20 °C

3.1: 3.15 g / sodium azide; tetra-n-butylammonium iodide / dimethylformamide / 1 h / 80 °C

4.1: triphenylphosphine / tetrahydrofuran; H₂O / 1 h / 20 °C

4.2: 53 percent / sodium carbonate / tetrahydrofuran; H₂O / 1 h / 20 °C

5.1: 980 mg / triphenylphosphine; diethyl azodicarboxylate / tetrahydrofuran; toluene / 0.17 h / 20 °C

6.1: trifluoroacetic acid / CH₂Cl₂ / 1 h / 0 °C

7.1: 1.09 g / triethylamine / dimethylformamide / 2 h / 20 °C

8.1: 52 percent / cesium carbonate; benzenethiol / acetonitrile / 0.5 h / 50 °C

With sodium azide; tetrabutyl ammonium fluoride; tetra-(n-butyl)ammonium iodide; caesium carbonate; thiophenol; triethylamine; triphenylphosphine; trifluoroacetic acid; diethylazodicarboxylate; In tetrahydrofuran; dichloromethane; water; N,N-dimethyl-formamide; toluene; acetonitrile; 5.1: Mitsunobu reaction;

DOI:10.1021/ol070376i

upstream raw materials:

C₃₇H₄₉F₃N₁₀O₁₁S₂

C₁₈H₃₂O₇SiSN₂

N-(2-[2-{2-hydroxyethoxy}ethoxy]ethyl)-2-nitro-benzenesulfonamide

(2-[2-azidoethoxy]ethyl)-N-nosylethanamine