methyl N-benzyl-O-((benzyloxy)methyl)-N-(tert-butoxycarbonyl)-L-serinate

Base Information

Chemical Name:methyl N-benzyl-O-((benzyloxy)methyl)-N-(tert-butoxycarbonyl)-L-serinate
CAS No.:158012-72-7
Molecular Formula:C₂₄H₃₁NO₆
Molecular Weight:429.513
Hs Code.:

Synonyms:methyl N-benzyl-O-((benzyloxy)methyl)-N-(tert-butoxycarbonyl)-L-serinate

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Chemical Property of methyl N-benzyl-O-((benzyloxy)methyl)-N-(tert-butoxycarbonyl)-L-serinate

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Technology Process of methyl N-benzyl-O-((benzyloxy)methyl)-N-(tert-butoxycarbonyl)-L-serinate

There total 5 articles about methyl N-benzyl-O-((benzyloxy)methyl)-N-(tert-butoxycarbonyl)-L-serinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 48.5%

: 3587-60-8
Benzyloxymethyl chloride

: 158012-71-6
methyl N-benzyl-N-(tert-butoxycarbonyl)-L-serinate

: 158012-72-7
methyl N-benzyl-O-((benzyloxy)methyl)-N-(tert-butoxycarbonyl)-L-serinate

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In dichloromethane; Ambient temperature;

Reference yield:

: 123639-56-5
(S)-N-benzylserine methyl ester

: 158012-72-7
methyl N-benzyl-O-((benzyloxy)methyl)-N-(tert-butoxycarbonyl)-L-serinate

Guidance literature:: Multi-step reaction with 2 steps

1: 70.8 percent / diethyl ether / Ambient temperature

2: 48.5 percent / diisopropylethylamine / CH₂Cl₂ / Ambient temperature

With N-ethyl-N,N-diisopropylamine; In diethyl ether; dichloromethane;

Reference yield:

: 40216-75-9
N-benzylidene-L-serine methyl ester

: 158012-72-7
methyl N-benzyl-O-((benzyloxy)methyl)-N-(tert-butoxycarbonyl)-L-serinate

Guidance literature:: Multi-step reaction with 3 steps

1: NaBH₄ / 0 °C

2: 70.8 percent / diethyl ether / Ambient temperature

3: 48.5 percent / diisopropylethylamine / CH₂Cl₂ / Ambient temperature

With sodium tetrahydroborate; N-ethyl-N,N-diisopropylamine; In diethyl ether; dichloromethane;