methyl (Z)-N-{2-[(trimethylsilyl)ethynyl]phenyl}benzimidate

Base Information

• Chemical Name: methyl (Z)-N-{2-[(trimethylsilyl)ethynyl]phenyl}benzimidate
• CAS No.: 1027223-95-5
• Molecular Formula: C₁₄H₁₂INO
• Molecular Weight: 337.16
• Mol file: 1027223-95-5.mol

Synonyms:methyl (Z)-N-{2-[(trimethylsilyl)ethynyl]phenyl}benzimidate

Chemical Property of methyl (Z)-N-{2-[(trimethylsilyl)ethynyl]phenyl}benzimidate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of methyl (Z)-N-{2-[(trimethylsilyl)ethynyl]phenyl}benzimidate

There total 1 articles about methyl (Z)-N-{2-[(trimethylsilyl)ethynyl]phenyl}benzimidate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

2-iodophenylamine (615-43-0) + orthobenzoic acid trimethyl ester (707-07-3) → methyl (Z)-N-{2-[(trimethylsilyl)ethynyl]phenyl}benzimidate (1027223-95-5)

Guidance literature:

With toluene-4-sulfonic acid; In toluene; for 16h; Reflux; Inert atmosphere;

DOI:10.1002/adsc.201400072

Reference yield: 99.0%

methyl (Z)-N-{2-[(trimethylsilyl)ethynyl]phenyl}benzimidate (1027223-95-5) + trimethylsilylacetylene (1066-54-2) → methyl (Z)-N-{2-[(trimethylsilyl)ethynyl]phenyl}benzimidate

Guidance literature:

With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine; In tetrahydrofuran; at 20 ℃; Inert atmosphere;

DOI:10.1002/adsc.201400072

Reference yield:

methyl (Z)-N-{2-[(trimethylsilyl)ethynyl]phenyl}benzimidate (1027223-95-5) + phenylacetylene (536-74-3) → C22H17NO

Guidance literature:

With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine; In tetrahydrofuran; Inert atmosphere;

DOI:10.1021/ol800202u

upstream raw materials:

2-iodophenylamine

orthobenzoic acid trimethyl ester

Downstream raw materials:

3-iodo-2-phenylquinolin-4-(1H)-one

3-iodo-2-(4'-methoxyphenyl)-quinolin-4(1H)-one

C₂₄H₁₉NO₃

6-iodo-8-methoxy-11,11-diphenylisoindolo[2,1-a]quinolin-5(11H)-one