phenyl 5-((4R,5R)-1-(4-hydroxy-[1,1'-biphenyl]-3-yl)-4-(phenoxycarbonyl)-4,5-dihydro-1H-imidazol-5-yl)oxazole-4-carboxylate

Base Information

Chemical Name:phenyl 5-((4R,5R)-1-(4-hydroxy-[1,1'-biphenyl]-3-yl)-4-(phenoxycarbonyl)-4,5-dihydro-1H-imidazol-5-yl)oxazole-4-carboxylate
CAS No.:1630973-63-5
Molecular Formula:C₃₂H₂₃N₃O₆
Molecular Weight:545.551
Hs Code.:

Synonyms:phenyl 5-((4R,5R)-1-(4-hydroxy-[1,1'-biphenyl]-3-yl)-4-(phenoxycarbonyl)-4,5-dihydro-1H-imidazol-5-yl)oxazole-4-carboxylate

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Chemical Property of phenyl 5-((4R,5R)-1-(4-hydroxy-[1,1'-biphenyl]-3-yl)-4-(phenoxycarbonyl)-4,5-dihydro-1H-imidazol-5-yl)oxazole-4-carboxylate

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Technology Process of phenyl 5-((4R,5R)-1-(4-hydroxy-[1,1'-biphenyl]-3-yl)-4-(phenoxycarbonyl)-4,5-dihydro-1H-imidazol-5-yl)oxazole-4-carboxylate

There total 2 articles about phenyl 5-((4R,5R)-1-(4-hydroxy-[1,1'-biphenyl]-3-yl)-4-(phenoxycarbonyl)-4,5-dihydro-1H-imidazol-5-yl)oxazole-4-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

: 1630972-64-3
6-phenyl-2H-benzo[b][1,4]oxazin-2-one

: 1630972-39-2
phenyl isocyanoacetate

: 1630973-63-5
phenyl 5-((4R,5R)-1-(4-hydroxy-[1,1'-biphenyl]-3-yl)-4-(phenoxycarbonyl)-4,5-dihydro-1H-imidazol-5-yl)oxazole-4-carboxylate

Guidance literature:: With C₃₉H₃₈N₃O₂P; silver(l) oxide; In tetrahydrofuran; at -20 - 0 ℃; for 24h; stereoselective reaction;
DOI:10.1002/anie.201402788

Reference yield:

: 1134-36-7
2-amino-4-phenylphenol

: 1630973-63-5
phenyl 5-((4R,5R)-1-(4-hydroxy-[1,1'-biphenyl]-3-yl)-4-(phenoxycarbonyl)-4,5-dihydro-1H-imidazol-5-yl)oxazole-4-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: toluene / 24 h / Molecular sieve; Reflux

2: C₃₉H₃₈N₃O₂P; silver(l) oxide / tetrahydrofuran / 24 h / -20 - 0 °C

With C₃₉H₃₈N₃O₂P; silver(l) oxide; In tetrahydrofuran; toluene;
DOI:10.1002/anie.201402788