Technology Process of 3,5-di(2-nitrobenzenesulfonyloxy)-4-methoxybenzoic acid
There total 4 articles about 3,5-di(2-nitrobenzenesulfonyloxy)-4-methoxybenzoic acid which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
tetrakis(triphenylphosphine) palladium(0); water; toluene-4-sulfonic acid;
In
tetrahydrofuran;
at 20 ℃;
for 1h;
DOI:10.1016/j.bmcl.2009.05.111
- Guidance literature:
-
Multi-step reaction with 3 steps
1: lithium carbonate / N,N-dimethyl-formamide / 20 h / 50 °C / Inert atmosphere
2: triethylamine / acetonitrile / 1.5 h / 0 °C / Inert atmosphere
3: sodium 4-methylbenzenesulfinate; tetrakis(triphenylphosphine) palladium(0); water / tetrahydrofuran / 1 h / 20 °C / Inert atmosphere
With
tetrakis(triphenylphosphine) palladium(0); water; lithium carbonate; sodium 4-methylbenzenesulfinate; triethylamine;
In
tetrahydrofuran; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1038/ja.2016.14
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; dmap / 4 h / 60 °C / Inert atmosphere
2: lithium carbonate / N,N-dimethyl-formamide / 20 h / 50 °C / Inert atmosphere
3: triethylamine / acetonitrile / 1.5 h / 0 °C / Inert atmosphere
4: sodium 4-methylbenzenesulfinate; tetrakis(triphenylphosphine) palladium(0); water / tetrahydrofuran / 1 h / 20 °C / Inert atmosphere
With
dmap; tetrakis(triphenylphosphine) palladium(0); water; lithium carbonate; sodium 4-methylbenzenesulfinate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine;
In
tetrahydrofuran; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1038/ja.2016.14
