(2R,3R)-(-)-methyl 3-bromo-2-hydroxy-3-phenylpropionate

Base Information

Chemical Name:(2R,3R)-(-)-methyl 3-bromo-2-hydroxy-3-phenylpropionate
CAS No.:117486-25-6
Molecular Formula:C₁₀H₁₁BrO₃
Molecular Weight:259.1
Hs Code.:

Synonyms:(2R,3R)-(-)-methyl 3-bromo-2-hydroxy-3-phenylpropionate

Suppliers and Price of (2R,3R)-(-)-methyl 3-bromo-2-hydroxy-3-phenylpropionate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2R,3R)-(-)-methyl 3-bromo-2-hydroxy-3-phenylpropionate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2R,3R)-(-)-methyl 3-bromo-2-hydroxy-3-phenylpropionate

There total 11 articles about (2R,3R)-(-)-methyl 3-bromo-2-hydroxy-3-phenylpropionate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 115794-67-7
methyl (2R,3S)-3-phenylglycidate

: 117486-25-6
(2R,3R)-(-)-methyl 3-bromo-2-hydroxy-3-phenylpropionate

Guidance literature:: With magnesium bromide; In diethyl ether; 1) -60 deg C, 2 h, 2) -40 deg C, 4 h;
DOI:10.1039/c39940002767

Reference yield:

: 4407-36-7
(2E)-3-phenyl-2-propen-1-ol

: 117486-25-6
(2R,3R)-(-)-methyl 3-bromo-2-hydroxy-3-phenylpropionate

Guidance literature:: Multi-step reaction with 3 steps

1: 87 percent / (+)-diisopropyl tartrate, Ti(OiPr)4, tBuOOH

2: 1) NaIO₄, RuCl₃ / 1) MeCN, CCl₄, H₂O

3: 98 percent / MgBr₂*Et₂O / diethyl ether / 1) -60 deg C, 2 h, 2) -40 deg C, 4 h

With titanium(IV) isopropylate; tert.-butylhydroperoxide; ruthenium trichloride; sodium periodate; L-(+)-diisopropyl tartrate; magnesium bromide; In diethyl ether;
DOI:10.1039/c39940002767

Reference yield:

: 19190-80-8,37161-74-3,40956-18-1,41603-34-3,99528-65-1,115794-66-6,115794-67-7,115794-68-8,130607-99-7
methyl trans-3-phenylglycidate

: 115723-78-9,117486-21-2,117486-25-6,117486-34-7,117497-28-6,145513-22-0,145513-23-1
threo-3-bromo-2-hydroxy-3-phenyl-propionic acid methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) HBr gas, 2.) Na₂CO₃ / 1.) C₆H₆, 1 h, 2.) H₂O, 50 deg C, 2 h

2: 58 percent Spectr_. / HBr gas / benzene / 1 h / 20 °C

With hydrogen bromide; sodium carbonate; In benzene;
DOI:10.1002/prac.19923340503