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α-Isocyano-p-tolylessigsaeureethylester

Base Information
  • Chemical Name:α-Isocyano-p-tolylessigsaeureethylester
  • CAS No.:39533-34-1
  • Molecular Formula:C12H13NO2
  • Molecular Weight:203.241
  • Hs Code.:
α-Isocyano-p-tolylessigsaeureethylester

Synonyms:α-Isocyano-p-tolylessigsaeureethylester

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Chemical Property of α-Isocyano-p-tolylessigsaeureethylester
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Technology Process of α-Isocyano-p-tolylessigsaeureethylester

There total 1 articles about α-Isocyano-p-tolylessigsaeureethylester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
With sodium hydride; In N,N-dimethyl-formamide;
DOI:10.1021/jo00951a030
Guidance literature:
With (S)-(2-(hydroxydiphenylmethyl)pyrrolidin-1-yl)(4-(pyrrolidin-1-yl)pyridin-3-yl)methanone; dibutylmagnesium; In n-heptane; toluene; at 40 ℃; for 12h; enantioselective reaction; Inert atmosphere;
DOI:10.1002/adsc.201900481
Guidance literature:
Multistep reaction; (i) aq. HCl, MeOH, (ii) NaOH;
DOI:10.1021/jo00951a030
upstream raw materials:

p-tolylmethyl isocyanide

Diethyl carbonate

Downstream raw materials:

2-amino-2-(4-methylphenyl)acetic acid

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