prop-2-yn-1-yl 2-deoxy-5-O-(4,4'-dimethoxytrityl)-β-D-ribofuranoside

Base Information

• Chemical Name: prop-2-yn-1-yl 2-deoxy-5-O-(4,4'-dimethoxytrityl)-β-D-ribofuranoside
• CAS No.: 1451958-56-7
• Molecular Formula: C₂₉H₃₀O₆
• Molecular Weight: 474.554
• Mol file: 1451958-56-7.mol

Synonyms:prop-2-yn-1-yl 2-deoxy-5-O-(4,4'-dimethoxytrityl)-β-D-ribofuranoside

Chemical Property of prop-2-yn-1-yl 2-deoxy-5-O-(4,4'-dimethoxytrityl)-β-D-ribofuranoside

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of prop-2-yn-1-yl 2-deoxy-5-O-(4,4'-dimethoxytrityl)-β-D-ribofuranoside

There total 1 articles about prop-2-yn-1-yl 2-deoxy-5-O-(4,4'-dimethoxytrityl)-β-D-ribofuranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

prop-2-yn-1-yl 2-deoxy-β-D-ribofuranoside (1451958-54-5) + 4,4'-dimethoxytrityl chloride (40615-36-9) → prop-2-yn-1-yl 2-deoxy-5-O-(4,4'-dimethoxytrityl)-β-D-ribofuranoside (1451958-56-7)

Guidance literature:

With pyridine; at 20 ℃; for 6h; Inert atmosphere;

DOI:10.1016/j.bmc.2013.05.034

Reference yield: 90.0%

prop-2-yn-1-yl 2-deoxy-5-O-(4,4'-dimethoxytrityl)-β-D-ribofuranoside (1451958-56-7) + 2-cyanoethyl-N,N-(diisopropylamino)chlorophosphine (124482-92-4,89992-70-1) → prop-2-yn-1-yl 3-O-[2-cyanoethoxy(diisopropylamino)phosphino]-2-deoxy-5-O-(4,4'-dimethoxytrityl)-β-D-ribofuranoside (1451958-58-9,1451958-61-4)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In dichloromethane; at 20 ℃; for 15h; Inert atmosphere;

DOI:10.1016/j.bmc.2013.05.034

upstream raw materials:

prop-2-yn-1-yl 2-deoxy-β-D-ribofuranoside

4,4'-dimethoxytrityl chloride

Downstream raw materials:

prop-2-yn-1-yl 3-O-[2-cyanoethoxy(diisopropylamino)phosphino]-2-deoxy-5-O-(4,4'-dimethoxytrityl)-β-D-ribofuranoside