N-(4-benzylbenzyl)cycloheptylamine

Base Information

• Chemical Name: N-(4-benzylbenzyl)cycloheptylamine
• CAS No.: 179055-77-7
• Molecular Formula: C₂₁H₂₇N
• Molecular Weight: 293.452
• Mol file: 179055-77-7.mol

Synonyms:N-(4-benzylbenzyl)cycloheptylamine

Chemical Property of N-(4-benzylbenzyl)cycloheptylamine

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of N-(4-benzylbenzyl)cycloheptylamine

There total 3 articles about N-(4-benzylbenzyl)cycloheptylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

4-(cycloheptylaminomethyl)benzophenone (179055-75-5) → N-(4-benzylbenzyl)cycloheptylamine (179055-77-7)

Guidance literature:

With potassium hydroxide; hydrazine hydrate; In ethylene glycol; at 150 - 200 ℃; for 9h;

DOI:10.1016/S0968-0896(97)10009-8

Reference yield:

4-Methylbenzophenone (134-84-9) → N-(4-benzylbenzyl)cycloheptylamine (179055-77-7)

Guidance literature:

Multi-step reaction with 3 steps

1: N-bromosuccinimide; benzoyl peroxide / CCl₄

3: 72 percent / KOH; H₂NNH₂*H₂O / ethane-1,2-diol / 9 h / 150 - 200 °C

With potassium hydroxide; N-Bromosuccinimide; hydrazine hydrate; dibenzoyl peroxide; In tetrachloromethane; ethylene glycol; 1: Bromination / 2: Alkylation / 3: Wolff-Kishner reduction;

DOI:10.1016/S0968-0896(97)10009-8

Reference yield:

4-(bromomethyl)benzophenone (32752-54-8) → N-(4-benzylbenzyl)cycloheptylamine (179055-77-7)

Guidance literature:

Multi-step reaction with 2 steps

2: 72 percent / KOH; H₂NNH₂*H₂O / ethane-1,2-diol / 9 h / 150 - 200 °C

With potassium hydroxide; hydrazine hydrate; In ethylene glycol; 1: Alkylation / 2: Wolff-Kishner reduction;

DOI:10.1016/S0968-0896(97)10009-8

upstream raw materials:

4-(cycloheptylaminomethyl)benzophenone

4-Methylbenzophenone

4-(bromomethyl)benzophenone