5-[4-(2-carboxyphenylcarbonylamino)-phenyl-4-carbonylmethylamino]-8-hydroxyquinoline

Base Information

Chemical Name:5-[4-(2-carboxyphenylcarbonylamino)-phenyl-4-carbonylmethylamino]-8-hydroxyquinoline
CAS No.:1414873-90-7
Molecular Formula:C₂₅H₁₉N₃O₅
Molecular Weight:441.443
Hs Code.:

Synonyms:5-[4-(2-carboxyphenylcarbonylamino)-phenyl-4-carbonylmethylamino]-8-hydroxyquinoline

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Chemical Property of 5-[4-(2-carboxyphenylcarbonylamino)-phenyl-4-carbonylmethylamino]-8-hydroxyquinoline

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Technology Process of 5-[4-(2-carboxyphenylcarbonylamino)-phenyl-4-carbonylmethylamino]-8-hydroxyquinoline

There total 3 articles about 5-[4-(2-carboxyphenylcarbonylamino)-phenyl-4-carbonylmethylamino]-8-hydroxyquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

: 85-44-9
phthalic anhydride

: 1414873-89-4
5-(4-phenylcarbonylmethylamino)-8-hydroxyquinoline

: 1414873-90-7
5-[4-(2-carboxyphenylcarbonylamino)-phenyl-4-carbonylmethylamino]-8-hydroxyquinoline

Guidance literature:: In acetone; at 10 ℃;
DOI:10.4067/S0717-97072012000400028

Reference yield:

: 3881-33-2
5-amino-8-hydroxyquinoline dihydrochloride

: 1414873-90-7
5-[4-(2-carboxyphenylcarbonylamino)-phenyl-4-carbonylmethylamino]-8-hydroxyquinoline

Guidance literature:: Multi-step reaction with 3 steps

1: acetone / 2.5 h / 20 °C

2: hydrogenchloride / ethanol

3: acetone / 10 °C

With hydrogenchloride; In ethanol; acetone;
DOI:10.4067/S0717-97072012000400028

Reference yield:

: 90798-25-7
N-[4-(chloroacetyl)phenyl]-2-chloroacetamide

: 1414873-90-7
5-[4-(2-carboxyphenylcarbonylamino)-phenyl-4-carbonylmethylamino]-8-hydroxyquinoline

Guidance literature:: Multi-step reaction with 3 steps

1: acetone / 2.5 h / 20 °C

2: hydrogenchloride / ethanol

3: acetone / 10 °C

With hydrogenchloride; In ethanol; acetone;
DOI:10.4067/S0717-97072012000400028