(S)-2-(((Benzyloxy)carbonyl)amino)-3,3-dimethylbutanoic acid

Base Information

Chemical Name:(S)-2-(((Benzyloxy)carbonyl)amino)-3,3-dimethylbutanoic acid
CAS No.:62965-10-0
Molecular Formula:C14H19NO4
Molecular Weight:265.309
Hs Code.:29225090
European Community (EC) Number:611-814-6,686-733-2
DSSTox Substance ID:DTXSID201341702
Nikkaji Number:J2.662.936E
Wikidata:Q76414749
Mol file:62965-10-0.mol

Synonyms:62965-10-0;Cbz-L-tert-Leucine;(S)-2-(((Benzyloxy)carbonyl)amino)-3,3-dimethylbutanoic acid;(2S)-2-{[(benzyloxy)carbonyl]amino}-3,3-dimethylbutanoic acid;59269-54-4;N-Benzyloxycarbonyl-L-tert-leucine;N-Benzyloxycarbonyl-tert-leucine;(2S)-2-([(BENZYLOXY)CARBONYL]AMINO)-3,3-DIMETHYLBUTANOIC ACID;(S)-2-(benzyloxycarbonylamino)-3,3-dimethylbutanoic acid;(2S)-3,3-dimethyl-2-(phenylmethoxycarbonylamino)butanoic acid;Z-Tle-OH;(2s)-2-{([benzyloxy)carbonyl]amino}-3,3-dimethylbutanoic acid;MFCD00137411;Cbz-Tle-OH;Z-tert-Leu-OH;Z-Tle;Z-L-T-Butylglycine;Cbz-(L)-tert-leucine;SCHEMBL738204;N-Benzyloxycarbonyl tert-leucine;NSVNKQLSGGKNKB-LLVKDONJSA-N;DTXSID201341702;HY-I0130;N-[(benzyloxy)carbonyl]-tert-leucine;AKOS005073798;AKOS015839333;N-benzyloxycarbonyl-3-methyl-L-valine;CS-W020724;SS-3079;(C2-H4-O)mult-C18-H30-O4-S.Na;AM20050385;3-Methyl-N-[(phenylmethoxy)carbonyl]-L-valine;EN300-122135;A834124;3-methyl-N-{[(phenylmethyl)oxy]carbonyl}-L-valine;J-502384;(S)-2-(CBZ-AMINO)-3,3-DIMETHYLBUTANOIC ACID;(S)-2-(((Benzyloxy)carbonyl)amino)-3,3-dimethylbutanoicacid

Suppliers and Price of (S)-2-(((Benzyloxy)carbonyl)amino)-3,3-dimethylbutanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Z-L-tert-leucine
1g
$ 259.00

TRC
Cbz-L-tert-Leucine
25g
$ 590.00

TRC
Cbz-L-tert-Leucine
2g
$ 80.00

SynQuest Laboratories
Cbz-L-tert-Leucine
250 mg
$ 200.00

SynQuest Laboratories
Cbz-L-tert-Leucine
1 g
$ 400.00

Matrix Scientific
(2S)-2-{[(Benzyloxy)carbonyl]amino}-3,3-dimethylbutanoic acid >90%
25g
$ 510.00

Matrix Scientific
(2S)-2-{[(Benzyloxy)carbonyl]amino}-3,3-dimethylbutanoic acid >90%
5g
$ 177.00

Matrix Scientific
(2S)-2-{[(Benzyloxy)carbonyl]amino}-3,3-dimethylbutanoic acid >90%
1g
$ 58.00

Crysdot
(S)-2-(((Benzyloxy)carbonyl)amino)-3,3-dimethylbutanoicacid 95+%
25g
$ 119.00

Chem-Impex
Z-L-tert-leucine
5G
$ 421.66

Total 74 raw suppliers

Chemical Property of (S)-2-(((Benzyloxy)carbonyl)amino)-3,3-dimethylbutanoic acid

Chemical Property:

Appearance/Colour:White powder
Vapor Pressure:0mmHg at 25°C
Refractive Index:1.528
Boiling Point:436.4 ºC at 760 mmHg
PKA:4.01±0.10(Predicted)
Flash Point:217.7 ºC
PSA：75.63000
Density:1.16 g/cm³
LogP:2.80300
Storage Temp.:Refrigerator
Solubility.:Chloroform (Sparingly), Methanol (Slightly)
XLogP3:2.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:6
Exact Mass:265.13140809
Heavy Atom Count:19
Complexity:316

Purity/Quality:

99% ^*data from raw suppliers

Z-L-tert-leucine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)C(C(=O)O)NC(=O)OCC1=CC=CC=C1
Isomeric SMILES:CC(C)(C)[C@@H](C(=O)O)NC(=O)OCC1=CC=CC=C1
Uses Cbz-L-tert-Leucine is a leucine derivative used in the preparation of various pharmaceutical agents such as TRPV4 antagonists, HIV-1 protease inhibitors and serine protease inhibitors.

Technology Process of (S)-2-(((Benzyloxy)carbonyl)amino)-3,3-dimethylbutanoic acid

There total 12 articles about (S)-2-(((Benzyloxy)carbonyl)amino)-3,3-dimethylbutanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%