methyl (S)-3-[4-(2-methylquinolin-4-ylmethoxy)-benzoylamino]-2-piperidin-1-ylpropanoate

Base Information

Chemical Name:methyl (S)-3-[4-(2-methylquinolin-4-ylmethoxy)-benzoylamino]-2-piperidin-1-ylpropanoate
CAS No.:1270808-99-5
Molecular Formula:C₂₇H₃₁N₃O₄
Molecular Weight:461.561
Hs Code.:

Synonyms:methyl (S)-3-[4-(2-methylquinolin-4-ylmethoxy)-benzoylamino]-2-piperidin-1-ylpropanoate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of methyl (S)-3-[4-(2-methylquinolin-4-ylmethoxy)-benzoylamino]-2-piperidin-1-ylpropanoate

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Technology Process of methyl (S)-3-[4-(2-methylquinolin-4-ylmethoxy)-benzoylamino]-2-piperidin-1-ylpropanoate

There total 2 articles about methyl (S)-3-[4-(2-methylquinolin-4-ylmethoxy)-benzoylamino]-2-piperidin-1-ylpropanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 1270808-98-4
methyl (S)-3-(4-hydroxybenzoylamino)-2-piperidin-1-ylpropanoate

: 288399-19-9
4-(chloromethyl)-2-methylquinoline

: 1270808-99-5
methyl (S)-3-[4-(2-methylquinolin-4-ylmethoxy)-benzoylamino]-2-piperidin-1-ylpropanoate

Guidance literature:: With potassium carbonate; potassium iodide; In butanone; at 80 ℃; for 18h;

Reference yield:

: 1270808-97-3
methyl (S)-3-[4-(2-methoxyethoxymethoxy)-benzoylamino]-2-piperidin-1-ylpropanoate

: 1270808-99-5
methyl (S)-3-[4-(2-methylquinolin-4-ylmethoxy)-benzoylamino]-2-piperidin-1-ylpropanoate

Guidance literature:: Multi-step reaction with 2 steps

1.1: sulfuric acid / tetrahydrofuran; methanol / 18 h / 35 °C

1.2: pH 8

2.1: potassium carbonate; potassium iodide / butanone / 18 h / 80 °C

With sulfuric acid; potassium carbonate; potassium iodide; In tetrahydrofuran; methanol; butanone;