3,4-Diamino-2-hydroxypyridine

Base Information

• Chemical Name: 3,4-Diamino-2-hydroxypyridine
• CAS No.: 33631-02-6
• Molecular Formula: C5H7 N3 O
• Molecular Weight: 125.13
• Hs Code.: 2933399090
• Mol file: 33631-02-6.mol

Synonyms:2-Pyridinol,3,4-diamino- (8CI); 3,4-Diamino-2-hydroxypyridine

Chemical Property of 3,4-Diamino-2-hydroxypyridine

Chemical Property:

• Vapor Pressure: 0.000471mmHg at 25°C
• Boiling Point: 545.7°Cat760mmHg
• Flash Point: 283.8°C
• PSA: 85.16000
• Density: 1.46g/cm³
• LogP: 1.11400
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature

Purity/Quality:

99% ^*data from raw suppliers

3,4-diaminopyridin-2-ol ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3,4-Diamino-2-hydroxypyridine

There total 7 articles about 3,4-Diamino-2-hydroxypyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

4-amino-3-nitro-pyridin-2-ol (88511-57-3) → 3,4-diamino-pyridin-2-ol (33631-02-6)

Guidance literature:

With hydrogen; 10% palladium on activated carbon; In DMF (N,N-dimethyl-formamide); at 20 ℃;

Reference yield:

3-amino-4-nitro-1H-pyridin-2-one → 3,4-diamino-1H-pyridin-2-one (33631-02-6)

Guidance literature:

With hydrogen; palladium 10% on activated carbon; In N,N-dimethyl-formamide; Heating / reflux;

Reference yield:

→ 3,4-diamino-pyridin-2-ol (33631-02-6)

Guidance literature:

With ethanol; nickel; Hydrogenation;

upstream raw materials:

4-amino-3-nitropyridine

imidazo<4,5-c>pyridine-4-one

4-amino-3-nitro-pyridin-2-ol

Downstream raw materials:

Imidazo<4,5-c>pyridin

pyrido[3,4-b]pyrazin-5(6H)-one

Refernces

• 1、 -. "New substituted imidazo-pyridinones and imidazo-pyridazinones, the preparation thereof and their use as pharmaceutical compositions". Page/Page column 16. . Retrieved 2008/06/13.