N-Acetyl-N-(phenylmethyl)-6-(3,5-dimethyl-4-oxo-2,5-cyclohexadien-1-ylidene)hex-1-enamine

Base Information

• Chemical Name: N-Acetyl-N-(phenylmethyl)-6-(3,5-dimethyl-4-oxo-2,5-cyclohexadien-1-ylidene)hex-1-enamine
• CAS No.: 149777-58-2
• Molecular Formula: C₂₃H₂₇NO₂
• Molecular Weight: 349.473
• Mol file: 149777-58-2.mol

Synonyms:N-Acetyl-N-(phenylmethyl)-6-(3,5-dimethyl-4-oxo-2,5-cyclohexadien-1-ylidene)hex-1-enamine

Chemical Property of N-Acetyl-N-(phenylmethyl)-6-(3,5-dimethyl-4-oxo-2,5-cyclohexadien-1-ylidene)hex-1-enamine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-Acetyl-N-(phenylmethyl)-6-(3,5-dimethyl-4-oxo-2,5-cyclohexadien-1-ylidene)hex-1-enamine

There total 5 articles about N-Acetyl-N-(phenylmethyl)-6-(3,5-dimethyl-4-oxo-2,5-cyclohexadien-1-ylidene)hex-1-enamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-Acetyl-N-(phenylmethyl)-6-(3,5-dimethyl-4-hydroxyphenyl)hex-1-enamine (149777-43-5) → N-Acetyl-N-(phenylmethyl)-6-(3,5-dimethyl-4-oxo-2,5-cyclohexadien-1-ylidene)hex-1-enamine (149777-58-2)

Guidance literature:

With silver(l) oxide;

DOI:10.1039/c39930000171

Reference yield:

6-<4-<(tert-butyldimethylsilyl)oxy>-3,5-dimethylphenyl>hexanal (144180-72-3) → N-Acetyl-N-(phenylmethyl)-6-(3,5-dimethyl-4-oxo-2,5-cyclohexadien-1-ylidene)hex-1-enamine (149777-58-2)

Guidance literature:

Multi-step reaction with 4 steps

1: MgSO₄ / CH₂Cl₂ / 3 h / Ambient temperature

2: pyridine, DMAP / benzene / 1.) 0 deg C, 5 min, 2.) room temp., overnight

3: n-Bu₄NF / tetrahydrofuran / 1 h / Ambient temperature

4: Ag₂O / CD₂Cl₂ / 0.42 h / Ambient temperature

With pyridine; dmap; tetrabutyl ammonium fluoride; magnesium sulfate; silver(l) oxide; In tetrahydrofuran; dichloromethane; dichloromethane-d2; benzene;

DOI:10.1021/jo00071a024

Reference yield:

Benzyl-[6-[4-(tert-butyl-dimethyl-silanyloxy)-3,5-dimethyl-phenyl]-hex-(Z)-ylidene]-amine → N-Acetyl-N-(phenylmethyl)-6-(3,5-dimethyl-4-oxo-2,5-cyclohexadien-1-ylidene)hex-1-enamine (149777-58-2)

Guidance literature:

Multi-step reaction with 3 steps

1: pyridine, DMAP / benzene / 1.) 0 deg C, 5 min, 2.) room temp., overnight

2: n-Bu₄NF / tetrahydrofuran / 1 h / Ambient temperature

3: Ag₂O / CD₂Cl₂ / 0.42 h / Ambient temperature

With pyridine; dmap; tetrabutyl ammonium fluoride; silver(l) oxide; In tetrahydrofuran; dichloromethane-d2; benzene;

DOI:10.1021/jo00071a024

upstream raw materials:

N-Acetyl-N-(phenylmethyl)-6-(3,5-dimethyl-4-hydroxyphenyl)hex-1-enamine

6-<4-<(tert-butyldimethylsilyl)oxy>-3,5-dimethylphenyl>hexanal

benzylamine