3'-Hydroxyacetophenone

Base Information Edit

Chemical Name:3'-Hydroxyacetophenone
CAS No.:121-71-1
Molecular Formula:C8H8O2
Molecular Weight:136.15
Hs Code.:29143990
European Community (EC) Number:204-494-0
NSC Number:2440
UNII:UV3GO1D90J
DSSTox Substance ID:DTXSID5059533
Nikkaji Number:J60.314G
Wikipedia:3-Hydroxyacetophenone
Wikidata:Q15410155
Metabolomics Workbench ID:133777
ChEMBL ID:CHEMBL404719
Mol file:121-71-1.mol

Synonyms:3'-hydroxyacetophenone

Suppliers and Price of 3'-Hydroxyacetophenone

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3’-Hydroxyacetophenone
5g
$ 55.00

TCI Chemical
3'-Hydroxyacetophenone >98.0%(GC)(T)
500g
$ 257.00

TCI Chemical
3'-Hydroxyacetophenone >98.0%(GC)(T)
25g
$ 30.00

SynQuest Laboratories
3-Hydroxyacetophenone
25 g
$ 24.00

SynQuest Laboratories
3-Hydroxyacetophenone
100 g
$ 47.00

Sigma-Aldrich
3′-Hydroxyacetophenone 97%
100g
$ 59.00

Sigma-Aldrich
3′-Hydroxyacetophenone ≥99%
5g
$ 55.30

Sigma-Aldrich
3′-Hydroxyacetophenone ≥99%
25g
$ 35.00

Sigma-Aldrich
3′-Hydroxyacetophenone 97%
25g
$ 41.90

Matrix Scientific
3'-Hydroxyacetophenone 95+%
100g
$ 39.00

Total 240 raw suppliers

Chemical Property of 3'-Hydroxyacetophenone Edit

Chemical Property:

Appearance/Colour:white crystal powder
Vapor Pressure:0.022Pa at 25℃
Melting Point:90-95 °C(lit.)
Refractive Index:1,534
Boiling Point:277 °C at 760 mmHg
PKA:9.19(at 25℃)
Flash Point:115.8 °C
PSA：37.30000
Density:1.10 g/cm³
LogP:1.59480
Storage Temp.:Store below +30°C.
Solubility.:22g/l
Water Solubility.:Soluble in alcohol. Insoluble in water.
XLogP3:1.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:136.052429494
Heavy Atom Count:10
Complexity:131

Purity/Quality:

99%+ ^*data from raw suppliers

3’-Hydroxyacetophenone ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn,Xi
Hazard Codes:Xn,Xi
Statements: 22-36/37/38
Safety Statements: 22-24/25-37/39-26-36

MSDS Files:: SDS file from LookChem

Useful:

Chemical Classes:Other Classes -> Aromatic Ketones
Canonical SMILES:CC(=O)C1=CC(=CC=C1)O
Description 3’-Hydroxyacetophenone is a chemical compound and it is a component of castoreum, the exudate from the castor sacs of the mature beaver. It is used in the synthesis and preparation of chalcones and flavonoids as anti-tuberculosis agents, as well as antileishmanial chaocones.
Uses 3’Hydroxyacetophenone is a chemical reagent used in the synthesis and preparation of chalcones and flavonoids as anti-tuberculosis agents, as well as antileishmanial chaocones. Useful in the preparation of chalcones, flavonoids, and phenylephrine. It is an active component of castoreum, which is used as a tincture in some perfumes and as a food additive. 3?Hydroxyacetophenone is used in the preparation of chalcones and flavonoids, which finds application as an anti-tuberculosis agent and antileishmanial chaocones. It is also involved in the preparation of phenylephrine. Further, it is an active component of castoreum, which is used as a tincture in some perfumes and as a food additive.

Technology Process of 3'-Hydroxyacetophenone

There total 63 articles about 3'-Hydroxyacetophenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 52600-91-6
1-(3-ethoxyphenyl)ethan-1-one

: 121-71-1
3-Hydroxyacetophenone

Guidance literature:: With 1-n-butyl-3-methylimidazolim bromide; at 200 - 220 ℃; for 0.5h; Microwave irradiation; Inert atmosphere;
DOI:10.5012/bkcs.2013.34.1.174

Reference yield: 98.0%

: 58621-54-8
1-(3-(allyloxy)phenyl)ethan-1-one

: 121-71-1
3-Hydroxyacetophenone

Guidance literature:: 1-(3-(allyloxy)phenyl)ethan-1-one; With bis(1,5-cyclooctadiene)nickel ⁽⁰⁾; diphenylsilane; 4,4'-di-tert-butyl-2,2'-bipyridine; In N,N-dimethyl-formamide; at 20 ℃; for 8h; Schlenk technique; Inert atmosphere; Sealed tube;

With hydrogenchloride; In water; N,N-dimethyl-formamide; at 50 ℃; for 2h; Reagent/catalyst; Schlenk technique; Inert atmosphere; Sealed tube;
DOI:10.1016/j.tetlet.2021.153341

Reference yield: 97.0%

: 3-acetylphenyl benzenesulfonate

: 121-71-1
3-Hydroxyacetophenone

Guidance literature:: With potassium hydroxide; In toluene; tert-butyl alcohol; at 100 ℃; for 0.5h; Inert atmosphere;
DOI:10.1080/00397911.2017.1393088