1,1-dimethylethyl2-((4R,6S)-6-((E)-2-(6-(4-fluorophenyl)-8-(1-methylethyl)-1-(methylsulfonyl)-1,2,3,5-tetrahydropyrido[2,3-e][1,4]oxazepin-7-yl)ethenyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate

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Chemical Name:1,1-dimethylethyl2-((4R,6S)-6-((E)-2-(6-(4-fluorophenyl)-8-(1-methylethyl)-1-(methylsulfonyl)-1,2,3,5-tetrahydropyrido[2,3-e][1,4]oxazepin-7-yl)ethenyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate
CAS No.:853181-74-5
Molecular Formula:C₃₂H₄₃FN₂O₇S
Molecular Weight:618.767
Hs Code.:

1,1-dimethylethyl2-((4R,6S)-6-((E)-2-(6-(4-fluorophenyl)-8-(1-methylethyl)-1-(methylsulfonyl)-1,2,3,5-tetrahydropyrido[2,3-e][1,4]oxazepin-7-yl)ethenyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate

Synonyms:1,1-dimethylethyl2-((4R,6S)-6-((E)-2-(6-(4-fluorophenyl)-8-(1-methylethyl)-1-(methylsulfonyl)-1,2,3,5-tetrahydropyrido[2,3-e][1,4]oxazepin-7-yl)ethenyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate

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Chemical Property of 1,1-dimethylethyl2-((4R,6S)-6-((E)-2-(6-(4-fluorophenyl)-8-(1-methylethyl)-1-(methylsulfonyl)-1,2,3,5-tetrahydropyrido[2,3-e][1,4]oxazepin-7-yl)ethenyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate

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Technology Process of 1,1-dimethylethyl2-((4R,6S)-6-((E)-2-(6-(4-fluorophenyl)-8-(1-methylethyl)-1-(methylsulfonyl)-1,2,3,5-tetrahydropyrido[2,3-e][1,4]oxazepin-7-yl)ethenyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate

There total 1 articles about 1,1-dimethylethyl2-((4R,6S)-6-((E)-2-(6-(4-fluorophenyl)-8-(1-methylethyl)-1-(methylsulfonyl)-1,2,3,5-tetrahydropyrido[2,3-e][1,4]oxazepin-7-yl)ethenyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 380460-37-7
[(4R,6S)-2,2-dimethyl-6-(1-phenyl-1H-tetrazole-5-sulfonylmethyl)[1,3]dioxan-4-yl]acetic acid tert-butyl ester

: 853181-72-3
6-(4-fluorophenyl)-8-(1-methylethyl)-1-(methylsulfonyl)-1,2,3,5-tetrahydropyrido[2,3-e][1,4]oxazepine-7-carboxaldehyde

: 853181-74-5
1,1-dimethylethyl2-((4R,6S)-6-((E)-2-(6-(4-fluorophenyl)-8-(1-methylethyl)-1-(methylsulfonyl)-1,2,3,5-tetrahydropyrido[2,3-e][1,4]oxazepin-7-yl)ethenyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate

Guidance literature:: With lithium hexamethyldisilazane; In tetrahydrofuran; at -78 ℃; for 0.5h;

Reference yield: 93.0%

: 853181-74-5
1,1-dimethylethyl2-((4R,6S)-6-((E)-2-(6-(4-fluorophenyl)-8-(1-methylethyl)-1-(methylsulfonyl)-1,2,3,5-tetrahydropyrido[2,3-e][1,4]oxazepin-7-yl)ethenyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate

: 7-[6-(4-fluorophenyl)-1,2,3,5-tetrahydro-8-(1-methylethyl)-1-(methylsulfonyl)pyrido[2,3-e][1,4]oxazepin-7-yl]-3,5-dihydroxy-(3R,5S,6E)-6-heptenoic acid, monosodium salt

Guidance literature:: 1,1-dimethylethyl2-((4R,6S)-6-((E)-2-(6-(4-fluorophenyl)-8-(1-methylethyl)-1-(methylsulfonyl)-1,2,3,5-tetrahydropyrido[2,3-e][1,4]oxazepin-7-yl)ethenyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate; With hydrogenchloride; water; In tetrahydrofuran; at 20 ℃; for 2h;

With sodium hydroxide; water; In tetrahydrofuran; methanol; for 2h;