C₂₆H₁₆F₆S₂

Base Information

• Chemical Name: C₂₆H₁₆F₆S₂
• CAS No.: 870677-95-5
• Molecular Formula: C₂₆H₁₆F₆S₂
• Molecular Weight: 506.535
• Mol file: 870677-95-5.mol

Synonyms:C₂₆H₁₆F₆S₂

Chemical Property of C₂₆H₁₆F₆S₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₆H₁₆F₆S₂

There total 5 articles about C₂₆H₁₆F₆S₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

1-[2,4-dimethyl-5-phenyl-3-thienyl]-2-[4-methyl-2,5-bis(trimethylsilylethynyl)-3-thienyl]hexafluorocyclopentene (868389-62-2) → C26H16F6S2 (870677-95-5)

Guidance literature:

With potassium hydroxide; In tetrahydrofuran; for 0.5h;

DOI:10.1021/ja053200p

Reference yield:

3-bromo-4-methylthiophene (30318-99-1) → C26H16F6S2 (870677-95-5)

Guidance literature:

Multi-step reaction with 5 steps

1.1: 92 percent / H₅IO₆; I₂; H₂SO₄ / aq. AcOH / 3 h / Heating

2.1: 42 percent / Pd(PPh₃)2Cl₂; Et₃N; CuI / 4 h / 60 °C

3.1: n-BuLi / tetrahydrofuran; hexane / 0.5 h / -78 °C

3.2: 79 percent / tetrahydrofuran; hexane / -78 - 10 °C

4.1: n-BuLi / tetrahydrofuran; hexane / 0.5 h / -78 °C

4.2: 76 percent / tetrahydrofuran; hexane / -78 - 10 °C

5.1: 86 percent / aq. KOH / tetrahydrofuran / 0.5 h

With bis-triphenylphosphine-palladium(II) chloride; potassium hydroxide; copper(l) iodide; n-butyllithium; sulfuric acid; iodine; periodic acid; triethylamine; acetic acid; In tetrahydrofuran; hexane; 2.1: Sonogashira coupling;

DOI:10.1021/ja053200p

Reference yield:

3-bromo-2,5-diiodo-4-methylthiophene (617689-00-6) → C26H16F6S2 (870677-95-5)

Guidance literature:

Multi-step reaction with 4 steps

1.1: 42 percent / Pd(PPh₃)2Cl₂; Et₃N; CuI / 4 h / 60 °C

2.1: n-BuLi / tetrahydrofuran; hexane / 0.5 h / -78 °C

2.2: 79 percent / tetrahydrofuran; hexane / -78 - 10 °C

3.1: n-BuLi / tetrahydrofuran; hexane / 0.5 h / -78 °C

3.2: 76 percent / tetrahydrofuran; hexane / -78 - 10 °C

4.1: 86 percent / aq. KOH / tetrahydrofuran / 0.5 h

With bis-triphenylphosphine-palladium(II) chloride; potassium hydroxide; copper(l) iodide; n-butyllithium; triethylamine; In tetrahydrofuran; hexane; 1.1: Sonogashira coupling;

DOI:10.1021/ja053200p

upstream raw materials:

1-[2,4-dimethyl-5-phenyl-3-thienyl]-2-[4-methyl-2,5-bis(trimethylsilylethynyl)-3-thienyl]hexafluorocyclopentene

3-bromo-2,5-diiodo-4-methylthiophene

3-bromo-4-methyl-2,5-bis(trimethylsilylethynyl)thiophene

1-[4-methyl-2,5-bis(trimethylsilylethynyl)-3-thienyl]heptafluorocyclopentene

Downstream raw materials:

1-[2,5-bis(4-formylphenylethynyl)-4-methyl-3-thienyl]-2-[2,4-dimethyl-5-phenyl-3-thienyl]hexafluorocyclopentene

1-[2,4-dimethyl-5-phenyl-3-thienyl]-2-[2,5-bis(3-(1-oxyl-3-oxide-4,4,5,5-tetramethylimidazolin-2-yl)phenylethynyl)-4-methyl-3-thienyl]hexafluorocyclopentene