C₁₄H₈BrClFNO

Base Information

• Chemical Name: C₁₄H₈BrClFNO
• CAS No.: 1369594-48-8
• Molecular Formula: C₁₄H₈BrClFNO
• Molecular Weight: 340.579
• Mol file: 1369594-48-8.mol

Synonyms:C₁₄H₈BrClFNO

Chemical Property of C₁₄H₈BrClFNO

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₄H₈BrClFNO

There total 3 articles about C₁₄H₈BrClFNO which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 35.0%

C14H9BrClNO (1369594-47-7) → C14H8BrClFNO (1369594-48-8)

Guidance literature:

With Select-F; In dimethyl sulfoxide; acetonitrile; at 0 - 20 ℃; for 2.5h;

Reference yield:

4'-bromo-2'-hydroxyacetophenone (30186-18-6) → C14H8BrClFNO (1369594-48-8)

Guidance literature:

Multi-step reaction with 3 steps

1: acetic acid / ethanol / 15 h / 90 °C

2: PPA / 2 h / 110 °C

3: diethylamino-sulfur trifluoride / acetonitrile; dimethyl sulfoxide / 2.5 h / 0 - 20 °C

With diethylamino-sulfur trifluoride; acetic acid; In ethanol; dimethyl sulfoxide; acetonitrile;

Reference yield:

C14H12BrClN2O (1369594-46-6) → C14H8BrClFNO (1369594-48-8)

Guidance literature:

Multi-step reaction with 2 steps

1: PPA / 2 h / 110 °C

2: diethylamino-sulfur trifluoride / acetonitrile; dimethyl sulfoxide / 2.5 h / 0 - 20 °C

With diethylamino-sulfur trifluoride; In dimethyl sulfoxide; acetonitrile;

upstream raw materials:

4'-bromo-2'-hydroxyacetophenone

C₁₄H₁₂BrClN₂O

C₁₄H₉BrClNO

Downstream raw materials:

C₄₅H₄₆F₃N₇O₅

C₃₃H₂₉ClF₂N₄O₃