endo-1-phenyl-1,1a,2,2a-tetrahydro-7H-cyclobutindene

Base Information

• Chemical Name: endo-1-phenyl-1,1a,2,2a-tetrahydro-7H-cyclobut
• Molecular Formula: C₁₇H₁₆
• Molecular Weight: 220.314

Synonyms:endo-1-phenyl-1,1a,2,2a-tetrahydro-7H-cyclobutindene

Chemical Property of endo-1-phenyl-1,1a,2,2a-tetrahydro-7H-cyclobut

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

There total 4 articles about endo-1-phenyl-1,1a,2,2a-tetrahydro-7H-cyclobutindene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

1-phenyl-1a,2a-dihydro-7H-cyclobutindene (138089-67-5) → endo-1-phenyl-1,1a,2,2a-tetrahydro-7H-cyclobutindene (72261-56-4)

Guidance literature:

With hydrogen; palladium on activated charcoal;

DOI:10.1021/ja00536a025

Reference yield:

1,1a,2,2a-tetrahydro-7H-cyclobutinden-1-one (31996-70-0) → endo-1-phenyl-1,1a,2,2a-tetrahydro-7H-cyclobutindene (72261-56-4)

Guidance literature:

Multi-step reaction with 4 steps

1: 93 percent / diethyl ether

2: 88 percent / phosphorus tribromide

3: 70 percent / 1,8-diazabicyclo<5.4.0>undec-7-ene / hexamethylphosphoric acid triamide / 10 h / 80 °C

4: 82 percent / hydrogen / 5percent palladium-carbon

With hydrogen; phosphorus tribromide; 1,8-diazabicyclo[5.4.0]undec-7-ene; palladium on activated charcoal; In N,N,N,N,N,N-hexamethylphosphoric triamide; diethyl ether;

DOI:10.1021/ja00536a025

Reference yield:

2,2-dichloro-7,7a-dihydro-2aH-cyclobuta[a]inden1-one (7316-61-2,20429-38-3) → endo-1-phenyl-1,1a,2,2a-tetrahydro-7H-cyclobutindene (72261-56-4)

Guidance literature:

Multi-step reaction with 5 steps

1: 77 percent / zinc

2: 93 percent / diethyl ether

3: 88 percent / phosphorus tribromide

4: 70 percent / 1,8-diazabicyclo<5.4.0>undec-7-ene / hexamethylphosphoric acid triamide / 10 h / 80 °C

5: 82 percent / hydrogen / 5percent palladium-carbon

With hydrogen; phosphorus tribromide; 1,8-diazabicyclo[5.4.0]undec-7-ene; zinc; palladium on activated charcoal; In N,N,N,N,N,N-hexamethylphosphoric triamide; diethyl ether;

DOI:10.1021/ja00536a025

upstream raw materials:

1-phenyl-1a,2a-dihydro-7H-cyclobutindene

1,1a,2,2a-tetrahydro-7H-cyclobutinden-1-one

2,2-dichloro-7,7a-dihydro-2aH-cyclobuta[a]inden1-one

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 72261-56-4 endo-1-phenyl-1,1a,2,2a-tetrahydro-7H-cyclobutindene

Send

Send

Metric Ton KG G Pound L ML

Send

Send