tert-butyl (E)-4-(2'-phenylcyclopropyl)-2,2-dimethyl-3-oxazolidinecarboxylate

Base Information

Chemical Name:tert-butyl (E)-4-(2'-phenylcyclopropyl)-2,2-dimethyl-3-oxazolidinecarboxylate
CAS No.:132639-30-6
Molecular Formula:C₁₉H₂₇NO₃
Molecular Weight:317.428
Hs Code.:

Synonyms:tert-butyl (E)-4-(2'-phenylcyclopropyl)-2,2-dimethyl-3-oxazolidinecarboxylate

Suppliers and Price of tert-butyl (E)-4-(2'-phenylcyclopropyl)-2,2-dimethyl-3-oxazolidinecarboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of tert-butyl (E)-4-(2'-phenylcyclopropyl)-2,2-dimethyl-3-oxazolidinecarboxylate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of tert-butyl (E)-4-(2'-phenylcyclopropyl)-2,2-dimethyl-3-oxazolidinecarboxylate

There total 7 articles about tert-butyl (E)-4-(2'-phenylcyclopropyl)-2,2-dimethyl-3-oxazolidinecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 132639-31-7
tert-butyl (E)-4-(2',2'-dibromo-3'-phenylcyclopropyl)-2,2-dimethyl-3-oxazolidinecarboxylate

: 132639-30-6
tert-butyl (E)-4-(2'-phenylcyclopropyl)-2,2-dimethyl-3-oxazolidinecarboxylate

Guidance literature:: With tri-n-butyl-tin hydride; In hexane; for 6h; Heating;
DOI:10.1016/S0040-4039(00)79491-3

Reference yield: 54.0%

: 591-50-4
iodobenzene

: 611234-39-0
(R)-2,2-Dimethyl-4-[(1R,2R)-2-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-cyclopropyl]-oxazolidine-3-carboxylic acid tert-butyl ester

: 132639-30-6
tert-butyl (E)-4-(2'-phenylcyclopropyl)-2,2-dimethyl-3-oxazolidinecarboxylate

Guidance literature:: With tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium tert-butylate; In 1,2-dimethoxyethane; tert-butyl alcohol; at 90 ℃; for 48h;
DOI:10.1002/ejoc.200300220

Reference yield:

: 1449-46-3
benzyltriphenylphosphonium bromide

: 132639-30-6
tert-butyl (E)-4-(2'-phenylcyclopropyl)-2,2-dimethyl-3-oxazolidinecarboxylate

Guidance literature:: Multi-step reaction with 3 steps

1: 1) n-BuLi / 1) hexane, 30 min, 2) 2 h

2: 74 percent / aq. NaOH (50percent), benzyltriethylammonium chloride / benzene; ethanol / 48 h / Ambient temperature

3: 97 percent / tributyltinhydride / hexane / 6 h / Heating

With sodium hydroxide; n-butyllithium; N-benzyl-N,N,N-triethylammonium chloride; tri-n-butyl-tin hydride; In ethanol; hexane; benzene;
DOI:10.1016/S0040-4020(01)88208-9