Methyl 5-formyl-1h-pyrazole-3-carboxylate

Base Information

Chemical Name:Methyl 5-formyl-1h-pyrazole-3-carboxylate
CAS No.:75436-40-7
Molecular Formula:C₆H₆N₂O₃
Molecular Weight:154.125
Hs Code.:
DSSTox Substance ID:DTXSID50504260
Wikidata:Q82358619
Mol file:75436-40-7.mol

Synonyms:75436-40-7;methyl 5-formyl-1h-pyrazole-3-carboxylate;methyl 3-formyl-1H-pyrazole-5-carboxylate;1H-Pyrazole-3-carboxylicacid, 5-formyl-, methyl ester;5-FORMYL-2H-PYRAZOLE-3-CARBOXYLIC ACID METHYL ESTER;SCHEMBL2628053;DTXSID50504260;AMY17371;MFCD17170014;AKOS015898273;SY264928

Suppliers and Price of Methyl 5-formyl-1h-pyrazole-3-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AK Scientific
Methyl5-formyl-1h-pyrazole-3-carboxylate
1g
$ 1403.00

Total 17 raw suppliers

Chemical Property of Methyl 5-formyl-1h-pyrazole-3-carboxylate

Chemical Property:

Boiling Point:373.803 °C at 760 mmHg
PKA:8.24±0.10(Predicted)
Flash Point:179.87 °C
PSA：72.05000
Density:1.394 g/cm³
LogP:0.00880
XLogP3:0.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:154.03784206
Heavy Atom Count:11
Complexity:171

Purity/Quality:

99% ^*data from raw suppliers

Methyl5-formyl-1h-pyrazole-3-carboxylate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)C1=NNC(=C1)C=O

Technology Process of Methyl 5-formyl-1h-pyrazole-3-carboxylate

There total 2 articles about Methyl 5-formyl-1h-pyrazole-3-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 75436-38-3
methyl 3-(dimethoxymethyl)-1H-pyrazole-5-carboxylate

: 1031351-93-5,75436-40-7
methyl 3-formyl-1H-pyrazole-5-carboxylate

Guidance literature:: With acetic acid; at 60 ℃; for 1h;
DOI:10.1016/j.bmc.2008.02.027

Reference yield:

: 75436-38-3
methyl 5-[bis(methyloxy)methyl]-1H-pyrazole-3-carboxylate

: 75436-40-7
5-Formyl-1H-pyrazole-3-carboxylic acid methyl ester

Guidance literature:: With formic acid; Yield given;
DOI:10.1016/0040-4039(80)80013-X

Reference yield:

: 1031351-93-5,75436-40-7
methyl 3-formyl-1H-pyrazole-5-carboxylate

: 1254966-50-1
C₂₉H₂₄FNOP⁽¹⁺⁾*Cl^(1-)

: 1254966-55-6
5-{(Z)-2-[3-(4-fluoro-phenyl)-5-methyl-isoxazol-4-yl]-vinyl}-2H-pyrazole-3-carboxylic acid methyl ester

: 1254966-54-5
5-{(E)-2-[3-(4-fluoro-phenyl)-5-methyl-isoxazol-4-yl]-vinyl}-2H-pyrazole-3-carboxylic acid methyl ester

Guidance literature:: C₂₉H₂₄FNOP⁽¹⁺⁾*Cl^(1-); With lithium hexamethyldisilazane; In tetrahydrofuran; at -78 - 20 ℃;

methyl 3-formyl-1H-pyrazole-5-carboxylate; In tetrahydrofuran; at 20 ℃;