6,7-dihydro-1,2,3,9-tetramethoxy-5H-dibenzocyclohepten-5-one

Base Information

• Chemical Name: 6,7-dihydro-1,2,3,9-tetramethoxy-5H-dibenzocyclohepten-5-one
• CAS No.: 127825-96-1
• Molecular Formula: C₁₉H₂₀O₅
• Molecular Weight: 328.365
• Mol file: 127825-96-1.mol

Synonyms:6,7-dihydro-1,2,3,9-tetramethoxy-5H-dibenzocyclohepten-5-one

Chemical Property of 6,7-dihydro-1,2,3,9-tetramethoxy-5H-dibenzocyclohepten-5-one

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 6,7-dihydro-1,2,3,9-tetramethoxy-5H-dibenzocyclohepten-5-one

There total 1 articles about 6,7-dihydro-1,2,3,9-tetramethoxy-5H-dibenzocyclohepten-5-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

2',3',4,4'-tetramethoxy-1,1'-biphenyl-2-propionic acid (127825-93-8) → 6,7-dihydro-1,2,3,9-tetramethoxy-5H-dibenzocyclohepten-5-one (127825-96-1) + 7-methoxy-4-(2',3',4'-trimethoxyphenyl)indan-1-one

Guidance literature:

With trifluoroacetic anhydride; In trifluoroacetic acid; for 10h; Ambient temperature;

DOI:10.1002/hlca.19890720805

Reference yield:

6,7-dihydro-1,2,3,9-tetramethoxy-5H-dibenzocyclohepten-5-one (127825-96-1) → 3,9,10,11-tetramethoxy-5H-dibenzo[a,c]cycloheptene (127825-89-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 84.5 percent / Na-borohydride / methanol / 2 h / Ambient temperature

2: 200 °C / vacuo

With sodium tetrahydroborate; In methanol;

DOI:10.1002/hlca.19890720805

Reference yield:

6,7-dihydro-1,2,3,9-tetramethoxy-5H-dibenzocyclohepten-5-one (127825-96-1) → deaminocolchinol methyl ether (4998-58-7)

Guidance literature:

Multi-step reaction with 3 steps

1: 84.5 percent / Na-borohydride / methanol / 2 h / Ambient temperature

2: 80.9 percent / 0.83 h / 190 - 200 °C / vacuo

3: 80 percent / H₂ / Pd / acetic acid / 12 h / 760 Torr / Ambient temperature

With sodium tetrahydroborate; hydrogen; palladium; In methanol; acetic acid;

DOI:10.1002/hlca.19890720805

upstream raw materials:

2',3',4,4'-tetramethoxy-1,1'-biphenyl-2-propionic acid

Downstream raw materials:

3,9,10,11-tetramethoxy-5H-dibenzo[a,c]cycloheptene

deaminocolchinol methyl ether