(E)-N-benzyl-N-[3-(1-dimethylsulfamoyl-1H-imidazol-4-yl)-2-propenyl]propenamide

Base Information

Chemical Name:(E)-N-benzyl-N-[3-(1-dimethylsulfamoyl-1H-imidazol-4-yl)-2-propenyl]propenamide
CAS No.:1300748-95-1
Molecular Formula:C₁₈H₂₂N₄O₃S
Molecular Weight:374.464
Hs Code.:

Synonyms:(E)-N-benzyl-N-[3-(1-dimethylsulfamoyl-1H-imidazol-4-yl)-2-propenyl]propenamide

Suppliers and Price of (E)-N-benzyl-N-[3-(1-dimethylsulfamoyl-1H-imidazol-4-yl)-2-propenyl]propenamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (E)-N-benzyl-N-[3-(1-dimethylsulfamoyl-1H-imidazol-4-yl)-2-propenyl]propenamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (E)-N-benzyl-N-[3-(1-dimethylsulfamoyl-1H-imidazol-4-yl)-2-propenyl]propenamide

There total 9 articles about (E)-N-benzyl-N-[3-(1-dimethylsulfamoyl-1H-imidazol-4-yl)-2-propenyl]propenamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

: 814-68-6,25189-84-8
acryloyl chloride

: 610768-37-1
N-benzyl-N-[(2E)-3-(1-dimethylsulfamoyl-1H-imidazol-4-yl)-2-propenyl]amine

: 1300748-95-1
(E)-N-benzyl-N-[3-(1-dimethylsulfamoyl-1H-imidazol-4-yl)-2-propenyl]propenamide

Guidance literature:: With triethylamine; In dichloromethane; at 0 - 20 ℃; for 3h; Inert atmosphere;
DOI:10.1039/c0ob00657b

Reference yield:

: 220378-49-4
C₈H₁₃N₃O₃S

: 1300748-95-1
(E)-N-benzyl-N-[3-(1-dimethylsulfamoyl-1H-imidazol-4-yl)-2-propenyl]propenamide

Guidance literature:: Multi-step reaction with 6 steps

1: thionyl chloride / dichloromethane / 0 - 20 °C / Inert atmosphere

2: N,N-dimethyl-formamide / 20 °C / Inert atmosphere

3: hydrazine hydrate / ethanol / 3 h / Inert atmosphere; Reflux

4: ethanol / 2 h / 20 °C / Inert atmosphere

5: sodium tetrahydroborate / ethanol / 0 - 20 °C / Inert atmosphere

6: triethylamine / dichloromethane / 3 h / 0 - 20 °C / Inert atmosphere

With sodium tetrahydroborate; thionyl chloride; hydrazine hydrate; triethylamine; In ethanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1039/c0ob00657b

Reference yield:

: 220378-46-1
methyl 3-(1-(N,N-dimethylsulfamoyl)imidazol-4-yl)-2-propenoate

: 1300748-95-1
(E)-N-benzyl-N-[3-(1-dimethylsulfamoyl-1H-imidazol-4-yl)-2-propenyl]propenamide

Guidance literature:: Multi-step reaction with 7 steps

1: diisobutylaluminium hydride

2: thionyl chloride / dichloromethane / 0 - 20 °C / Inert atmosphere

3: N,N-dimethyl-formamide / 20 °C / Inert atmosphere

4: hydrazine hydrate / ethanol / 3 h / Inert atmosphere; Reflux

5: ethanol / 2 h / 20 °C / Inert atmosphere

6: sodium tetrahydroborate / ethanol / 0 - 20 °C / Inert atmosphere

7: triethylamine / dichloromethane / 3 h / 0 - 20 °C / Inert atmosphere

With sodium tetrahydroborate; thionyl chloride; diisobutylaluminium hydride; hydrazine hydrate; triethylamine; In ethanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1039/c0ob00657b