Technology Process of C22H31BrO4
There total 5 articles about C22H31BrO4 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
triethylamine; phosphonic acid diethyl ester;
In
N,N-dimethyl-formamide;
at 20 ℃;
for 2h;
DOI:10.1016/j.bmcl.2012.04.062
- Guidance literature:
-
Multi-step reaction with 2 steps
1: triphenylphosphine; zinc / dichloromethane / 1.5 h / 20 °C
2: triethylamine; phosphonic acid diethyl ester / N,N-dimethyl-formamide / 2 h / 20 °C
With
triethylamine; phosphonic acid diethyl ester; triphenylphosphine; zinc;
In
dichloromethane; N,N-dimethyl-formamide;
1: Ramirez olefination reaction;
DOI:10.1016/j.bmcl.2012.04.062
- Guidance literature:
-
Multi-step reaction with 8 steps
1.1: sodium hydride / N,N-dimethyl-formamide / 12 h / 20 °C
2.1: lithium aluminium tetrahydride / tetrahydrofuran / 2 h / 20 °C
3.1: 1H-imidazole; dmap / 5 h / 20 °C
4.1: n-butyllithium / tetrahydrofuran / 0.5 h / 0 °C
4.2: 6 h / 20 °C
5.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 1 h / 20 °C
6.1: pyridinium chlorochromate / dichloromethane / 3 h / 20 °C / Molecular sieve
7.1: triphenylphosphine; zinc / dichloromethane / 1.5 h / 20 °C
8.1: triethylamine; phosphonic acid diethyl ester / N,N-dimethyl-formamide / 2 h / 20 °C
With
1H-imidazole; dmap; lithium aluminium tetrahydride; n-butyllithium; tetrabutyl ammonium fluoride; sodium hydride; triethylamine; phosphonic acid diethyl ester; triphenylphosphine; pyridinium chlorochromate; zinc;
In
tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;
7.1: Ramirez olefination reaction;
DOI:10.1016/j.bmcl.2012.04.062
