(1S,5S)-2,4,4-trimethylbicyclo<3.2.1>oct-2-en-7-one p-toluenesulfonylhydrazone

Base Information

• Chemical Name: (1S,5S)-2,4,4-trimethylbicyclo<3.2.1>oct-2-en-7-one p-toluenesulfonylhydrazone
• CAS No.: 110355-09-4
• Molecular Formula: C₁₈H₂₄N₂O₂S
• Molecular Weight: 332.467
• Mol file: 110355-09-4.mol

Synonyms:(1S,5S)-2,4,4-trimethylbicyclo<3.2.1>oct-2-en-7-one p-toluenesulfonylhydrazone

Chemical Property of (1S,5S)-2,4,4-trimethylbicyclo<3.2.1>oct-2-en-7-one p-toluenesulfonylhydrazone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (1S,5S)-2,4,4-trimethylbicyclo<3.2.1>oct-2-en-7-one p-toluenesulfonylhydrazone

There total 2 articles about (1S,5S)-2,4,4-trimethylbicyclo<3.2.1>oct-2-en-7-one p-toluenesulfonylhydrazone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 48.0%

(1S,5S)-2,4,4-trimethylbicyclo<3.2.1>oct-2-en-7-one (110415-93-5) + toluene-4-sulfonic acid hydrazide (1576-35-8) → (1R,5S)-2,8,8-trimethylbicyclo<3.2.1>oct-2-en-7-one (110415-92-4) + (1S,5S)-2,4,4-trimethylbicyclo<3.2.1>oct-2-en-7-one p-toluenesulfonylhydrazone (110355-09-4)

Guidance literature:

In ethanol; for 1.5h; Heating;

DOI:10.1021/ja00255a005

Reference yield:

(-)-α-pinene (7785-26-4,25766-18-1) + toluene-4-sulfonic acid hydrazide (1576-35-8) → (1R,5S)-2,8,8-trimethylbicyclo<3.2.1>oct-2-en-7-one (110415-92-4) + (1S,5S)-2,4,4-trimethylbicyclo<3.2.1>oct-2-en-7-one p-toluenesulfonylhydrazone (110355-09-4)

Guidance literature:

Yield given. Multistep reaction. Yields of byproduct given; 1.) 175 deg C, 53 h, 2.) 95percent ethanol, reflux, 1.5 h;

DOI:10.1021/ja00255a005

upstream raw materials:

(1S,5S)-2,4,4-trimethylbicyclo<3.2.1>oct-2-en-7-one

toluene-4-sulfonic acid hydrazide

(-)-α-pinene