cis-(1S,4S)-N-methyl-(3-chlorophenyl)-1,2,3,4-tetrahydro-1-naphtalenamine

Base Information

• Chemical Name: cis-(1S,4S)-N-methyl-(3-chlorophenyl)-1,2,3,4-tetrahydro-1-naphtalenamine
• CAS No.: 871838-58-3
• Molecular Formula: C₁₇H₁₈ClN
• Molecular Weight: 271.79
• Mol file: 871838-58-3.mol

Synonyms:cis-(1S,4S)-N-methyl-(3-chlorophenyl)-1,2,3,4-tetrahydro-1-naphtalenamine

Chemical Property of cis-(1S,4S)-N-methyl-(3-chlorophenyl)-1,2,3,4-tetrahydro-1-naphtalenamine

Chemical Property:

Purity/Quality:

99%min. ^*data from raw suppliers

(rac,syn)-4-Deschloro-sertraline ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: (rac,syn)-4-Deschloro-sertraline is the analog of sertraline, a selective serotonin reuptake inhibitor. Used as an antidepressant.

Technology Process of cis-(1S,4S)-N-methyl-(3-chlorophenyl)-1,2,3,4-tetrahydro-1-naphtalenamine

There total 1 articles about cis-(1S,4S)-N-methyl-(3-chlorophenyl)-1,2,3,4-tetrahydro-1-naphtalenamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-[4-(3,4-dichlorophenyl)-3,4-dihydro-1(2H)-naphthalenylidene]methanamine (79560-20-6) → cis-(1S,4S)-N-methyl-(3-chlorophenyl)-1,2,3,4-tetrahydro-1-naphtalenamine (871838-58-3) + cis-(1S,4S)-N-methyl-(4-chlorophenyl)-1,2,3,4-tetrahydro-1-naphtalenamine (91797-63-6,91742-83-5) + 4-(3,4-dichlorophenyl)-3,4-dihydro-2H-naphthalen-1-one (79560-19-3,79836-44-5) + trans-(1S,4R)-N-methyl-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthalenamine (91797-60-3) + Sertraline (79617-96-2)

Guidance literature:

With hydrogen; SA-3135 support, Co(NO₃)2, H₂O; dried and calcined ones or twice (Co 11 - 25percent); reduction with H₂; In tetrahydrofuran; at 120 - 150 ℃; under 6000.6 Torr;

upstream raw materials:

N-[4-(3,4-dichlorophenyl)-3,4-dihydro-1(2H)-naphthalenylidene]methanamine

Refernces