Technology Process of 9-N-p-methoxybenzyl-1-methylguanine
There total 3 articles about 9-N-p-methoxybenzyl-1-methylguanine which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
potassium carbonate;
In
dimethyl sulfoxide;
at 20 ℃;
for 26h;
Inert atmosphere;
DOI:10.1021/ol400752s
- Guidance literature:
-
Multi-step reaction with 2 steps
1: hydrogenchloride / water / 1.5 h / 100 °C
2: potassium carbonate / dimethyl sulfoxide / 26 h / 20 °C / Inert atmosphere
With
hydrogenchloride; potassium carbonate;
In
water; dimethyl sulfoxide;
DOI:10.1021/ol400752s
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: sodium hydride / dimethyl sulfoxide / 1.25 h / 20 °C / Inert atmosphere
1.2: 5 h / 23 °C
2.1: hydrogenchloride / water / 1.5 h / 100 °C
3.1: potassium carbonate / dimethyl sulfoxide / 26 h / 20 °C / Inert atmosphere
With
hydrogenchloride; sodium hydride; potassium carbonate;
In
water; dimethyl sulfoxide;
DOI:10.1021/ol400752s
