1-Hydroxybenzotriazole hydrate

Base Information

• Chemical Name: 1-Hydroxybenzotriazole hydrate
• CAS No.: 123333-53-9
• Molecular Formula: 2C₆H₅N₃O*H₂O
• Molecular Weight: 288.266
• Hs Code.: 29339980
• European Community (EC) Number: 602-929-2,806-689-1
• UNII: S72K7GY45F
• DSSTox Substance ID: DTXSID30924462
• Wikidata: Q27288752
• Mol file: 123333-53-9.mol

Synonyms:1-Hydroxybenzotriazole hydrate;123333-53-9;80029-43-2;1h-1,2,3-benzotriazol-1-ol hydrate;1-hydroxybenzotriazole monohydrate;1-hydroxybenzotriazole;hydrate;1h-benzo[d][1,2,3]triazol-1-ol hydrate;1H-Benzotriazole, 1-hydroxy-, monohydrate;1-Hydroxybenzotriazolehydrate;1H-Benzo[d][1,2,3]triazol-1-ol xhydrate;HOBT.H2O;UNII-S72K7GY45F;S72K7GY45F;1-Hydroxy-1H-benzotriazole monohydrate [MI];1-Hydroxybenzotriazolemonohydrate;1H-Benzotriazole, 1-hydroxy-, hydrate (1:1);1H-benzo[d][1,2,3]triazol-1-ol monohydrate;HOBt Hydrate;1-Hydroxybenzotriazole hydrate wetted with not less than 20 wt. % water < 25 ppm hydrazine;hobt monohydrate;n-hydroxybenzotriazole monohydrate;hobt h2o;1-hydroxy benzotriazole monohydrate;1,2,3-benzotriazol-1-ol monohydrate;benzotriazol-1-ol hydrate;n-hydroxybenzotriazole h2o;benzotriazole-1-ol hydrate;N-Hydroxybenzotriazole.H2O;1-hydroxybenzotriazole H2O;1-hydroxybenzotriazol hydrat;SCHEMBL5523;1hydroxybenzotriazole hydrate;N-hydroxybenzotriazol hydrate;1-hydoxybenzotriazole hydrate;1-hydroxybenzotriazol hydrate;1-hydroxybenzotriazol-hydrate;1-hydroxybenztriazole hydrate;1-hydroxybezotriazole hydrate;1-hyroxybenzotriazole hydrate;benzotriazol-1-ol monohydrate;1-hydroxybenzotriazole-hydrate;1-hyrdoxybenzotriazole hydrate;3-hydroxybenzotriazole hydrate;1H-benzotriazol-1-ol hydrate;1 -hydroxybenztriazole hydrate;1-hydoxybenzo-triazole hydrate;1-hydroxy benzotriazol hydrate;1-hydroxy-benzotriazol hydrate;1-Hydroxylbenzotriazole hydrate;N-hydroxybenzo-triazole hydrate;1 -hydroxybenzotriazole hydrate;1-hydroxy benzotriazole hydrate;1-Hydroxy-benzotriazole hydrate;1-hydroxybenzo-triazole hydrate;N-hydroxy-benztriazole. hydrate;1-hydroxybenzotriazol monohydrate;1-hydroxybenztriazole monohydrate;HOBt hydrate wetted with not less than 20 wt. % water;1-Hydroxybenzotriazole - hydrate;1-hydroxybenzotriazole-monohydrate;DTXSID30924462;1-hydroxybenztriazole mono-hydrate;PJUPKRYGDFTMTM-UHFFFAOYSA-N;1-hydroxy-1H-benzotriazol hydrate;1-hydroxy-benzotriazole monohydrate;1-hydroxybenzo-triazole monohydrate;1-hydroxyl benzotriazole monohydrate;BCP25462;1-hydroxy-1h-benzo-triazole hydrate;AC-493;MFCD00065690;SH-001;1-hydroxy-1H-benzotriazol monohydrate;1-hydroxy-1H-benztriazole monohydrate;1H-1,2,3-benzotriazol-1-olhydrate;AKOS008901139;1-hydroxy-1H-benzotriazole monohydrate;1-hydroxy-1H-benzotriazole-monohydrate;1H-Benzotriazol-1-ol--water (1/1);AM83834;1,2,3-benzotriazole-1-ol, monohydrate;1-hydroxy-1,2,3-benzotriazole hydrate;1H-1,2,3-benzotriazol-1-ol monohydrate;1-hydroxy-1H-1,2,3-benzotriazole hydrate;1H-Benzotriazole 1-hydroxy-hydrate (9CI);1H-benzo[d][1,2,3]-triazol-1-ol hydrate;FT-0602216;FT-0607863;FT-0607915;1-Hydroxybenzotriazole hydrate (HOBT hydrate);1H-benzo-[d][1,2,3]-triazol-1-ol hydrate;1H-Benzotriazole, 1-hydroxy-, hydrate (1:);1-hydroxy-1H-1,2,3-benzotriazole monohydrate;1-Hydroxybenzotriazole hydrate, >=97.0% (T);1h-benzotriazol, 1-hidroxi-, hidrato (1:?);M02875;A805049;J-504792;W-200965;Q27288752;F0001-0374;1-Hydroxybenzotriazole hydrate, wetted with not less than 14 wt. % water, 97%;1-Hydroxybenzotriazole hydrate, wetted with not less than 20 wt. % water, 97%;1-hydroxybenzotriazole hydrate;HOBT hydrate wetted with not less than 20 wt. % water;TIMTEC-BB SBB000114 N-HYDROXYBENZOTRIAZOLE H2O N-HYDROXYBENZOTRIAZOLE HYDRATE N-HYDROXYBENZOTRIAZOLE MONOHYDRATE

Chemical Property of 1-Hydroxybenzotriazole hydrate

Chemical Property:

• Appearance/Colour: White to off-white powder
• Vapor Pressure: 3.28E-05mmHg at 25°C
• Melting Point: 155-158°C(lit.)
• Refractive Index: 1.6910 (estimate)
• Boiling Point: 344.6oC at 760mmHg
• Flash Point: 162.2oC
• PSA: 50.94000
• Density: 1.065 g/cm
• LogP: 0.66860
• Storage Temp.: Store at RT.
• Solubility.: DMF: 100 mg/mL, clear
• Water Solubility.: slightly soluble
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 0
• Exact Mass: 153.053826475
• Heavy Atom Count: 11
• Complexity: 130

Purity/Quality:

99.0% ^*data from raw suppliers

1-Hydroxybenzotriazole hydrate ^*data from reagent suppliers

Safty Information:

• Pictogram(s): R11:; R5:
• Hazard Codes: F
• Statements: 5-11-R5-R11-44-1
• Safety Statements: 15-16-35-7/9-33-S7/9-S33-S16-60-37-26

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Nitrogen Compounds -> Triazoles
• Canonical SMILES: C1=CC=C2C(=C1)N=NN2O.O
• Uses: additive for oligonucleotide couplings and in racemization-free peptide couplings 1-Hydroxybenzotriazole hydrate can be used as a condensation reagent to prepare: Poly-γ-glutamic acid methyl ester from a dimer of γ-glutamic acid. Oxadiazoles via cyclo condensation of amidoximes with trifluoroacetic anhydride or benzoic acid derivatives. A common additive for peptide coupling.