p-chlorophenyl 2,3-di-O-acetyl-4,6-O-benzylidene-β-D-galactopyranosyl-(1->4)-3,6-di-O-benzyl-2-deoxy-2-phthalimido-1-thio-β-D-glucopyranoside

Base Information

Chemical Name:p-chlorophenyl 2,3-di-O-acetyl-4,6-O-benzylidene-β-D-galactopyranosyl-(1->4)-3,6-di-O-benzyl-2-deoxy-2-phthalimido-1-thio-β-D-glucopyranoside
CAS No.:1385090-43-6
Molecular Formula:C₅₁H₄₈ClNO₁₃S
Molecular Weight:950.46
Hs Code.:

Synonyms:p-chlorophenyl 2,3-di-O-acetyl-4,6-O-benzylidene-β-D-galactopyranosyl-(1->4)-3,6-di-O-benzyl-2-deoxy-2-phthalimido-1-thio-β-D-glucopyranoside

Suppliers and Price of p-chlorophenyl 2,3-di-O-acetyl-4,6-O-benzylidene-β-D-galactopyranosyl-(1->4)-3,6-di-O-benzyl-2-deoxy-2-phthalimido-1-thio-β-D-glucopyranoside

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of p-chlorophenyl 2,3-di-O-acetyl-4,6-O-benzylidene-β-D-galactopyranosyl-(1->4)-3,6-di-O-benzyl-2-deoxy-2-phthalimido-1-thio-β-D-glucopyranoside

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of p-chlorophenyl 2,3-di-O-acetyl-4,6-O-benzylidene-β-D-galactopyranosyl-(1->4)-3,6-di-O-benzyl-2-deoxy-2-phthalimido-1-thio-β-D-glucopyranoside

There total 3 articles about p-chlorophenyl 2,3-di-O-acetyl-4,6-O-benzylidene-β-D-galactopyranosyl-(1->4)-3,6-di-O-benzyl-2-deoxy-2-phthalimido-1-thio-β-D-glucopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 1385090-38-9
p-chlorophenyl 3,6-di-O-benzyl-2-deoxy-2-phthalimido-1-thio-β-D-glucopyranoside

: 129753-04-4
O-(2,3-di-O-acetyl-4,6-O-benzylidene-α-D-galactopyranosyl) trichloroacetimidate

: 1385090-43-6
p-chlorophenyl 2,3-di-O-acetyl-4,6-O-benzylidene-β-D-galactopyranosyl-(1->4)-3,6-di-O-benzyl-2-deoxy-2-phthalimido-1-thio-β-D-glucopyranoside

Guidance literature:: p-chlorophenyl 3,6-di-O-benzyl-2-deoxy-2-phthalimido-1-thio-β-D-glucopyranoside; O-(2,3-di-O-acetyl-4,6-O-benzylidene-α-D-galactopyranosyl) trichloroacetimidate; In dichloromethane; at 20 ℃; for 2h; Molecular sieve; Inert atmosphere;

With boron trifluoride diethyl etherate; In dichloromethane; at -72 - 20 ℃; for 16h; pH=3; Molecular sieve; Inert atmosphere;
DOI:10.1021/jo300764k

Reference yield:

: 1385090-31-2
p-chlorophenyl 3-O-benzyl-4,6-O-benzylidene-2-deoxy-2-N-phthalimido-1-thio-β-D-glucopyranoside

: 1385090-43-6
p-chlorophenyl 2,3-di-O-acetyl-4,6-O-benzylidene-β-D-galactopyranosyl-(1->4)-3,6-di-O-benzyl-2-deoxy-2-phthalimido-1-thio-β-D-glucopyranoside

Guidance literature:: Multi-step reaction with 2 steps

1.1: triethylsilane; boron trifluoride diethyl etherate / dichloromethane / 3.5 h / 0 °C

2.1: dichloromethane / 2 h / 20 °C / Molecular sieve; Inert atmosphere

2.2: 16 h / -72 - 20 °C / pH 3 / Molecular sieve; Inert atmosphere

With triethylsilane; boron trifluoride diethyl etherate; In dichloromethane;
DOI:10.1021/jo300764k

Reference yield:

: 296768-93-9
4-chlorophenyl 4,6-O-benzylidene-2-deoxy-2-phthalimido-1-thio-β-D-glucopyranoside

: 1385090-43-6
p-chlorophenyl 2,3-di-O-acetyl-4,6-O-benzylidene-β-D-galactopyranosyl-(1->4)-3,6-di-O-benzyl-2-deoxy-2-phthalimido-1-thio-β-D-glucopyranoside

Guidance literature:: Multi-step reaction with 3 steps

1.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0.5 h

2.1: triethylsilane; boron trifluoride diethyl etherate / dichloromethane / 3.5 h / 0 °C

3.1: dichloromethane / 2 h / 20 °C / Molecular sieve; Inert atmosphere

3.2: 16 h / -72 - 20 °C / pH 3 / Molecular sieve; Inert atmosphere

With triethylsilane; boron trifluoride diethyl etherate; sodium hydride; In dichloromethane; N,N-dimethyl-formamide; mineral oil;
DOI:10.1021/jo300764k