N-[3-(2,4-difluorophenyl)-2-oxopiperidin-1-yl]-3-p-tolylsulfanylpropionamide

Base Information

Chemical Name:N-[3-(2,4-difluorophenyl)-2-oxopiperidin-1-yl]-3-p-tolylsulfanylpropionamide
CAS No.:1240469-40-2
Molecular Formula:C₂₁H₂₂F₂N₂O₂S
Molecular Weight:404.481
Hs Code.:

Synonyms:N-[3-(2,4-difluorophenyl)-2-oxopiperidin-1-yl]-3-p-tolylsulfanylpropionamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-[3-(2,4-difluorophenyl)-2-oxopiperidin-1-yl]-3-p-tolylsulfanylpropionamide

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Technology Process of N-[3-(2,4-difluorophenyl)-2-oxopiperidin-1-yl]-3-p-tolylsulfanylpropionamide

There total 1 articles about N-[3-(2,4-difluorophenyl)-2-oxopiperidin-1-yl]-3-p-tolylsulfanylpropionamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1240469-39-9
1-amino-3-(2,4-difluorophenyl)piperidin-2-one

: 13739-35-0
3-[(4-methylphenyl)thio]propionic acid

: 1240469-40-2
N-[3-(2,4-difluorophenyl)-2-oxopiperidin-1-yl]-3-p-tolylsulfanylpropionamide

Guidance literature:: With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 20 ℃; for 27h;

Reference yield:

: 1240469-40-2
N-[3-(2,4-difluorophenyl)-2-oxopiperidin-1-yl]-3-p-tolylsulfanylpropionamide

: 1240469-41-3
8-(2,4-difluorophenyl)-2-(2-p-tolylsulfanylethyl)-5,6,7,8-tetrahydro[1,2.4]triazolo[1,5-a]pyridine

Guidance literature:: N-[3-(2,4-difluorophenyl)-2-oxopiperidin-1-yl]-3-p-tolylsulfanylpropionamide; With trichlorophosphate; at 120 ℃; for 1h;

With ammonium acetate; acetic acid; at 150 ℃; for 2.5h;

With ammonia; In water; ethyl acetate;