Technology Process of 2,4-dimethoxy-1-(2-methyl-propenyl)-benzene
There total 1 articles about 2,4-dimethoxy-1-(2-methyl-propenyl)-benzene which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
isopropyltriphenylphosphonium iodide;
With
n-butyllithium;
In
tetrahydrofuran; hexane;
at 0 ℃;
for 0.5h;
2,4-Dimethoxybenzaldehyde;
In
tetrahydrofuran; hexane;
at 20 ℃;
for 4h;
DOI:10.1021/ol048462v
- Guidance literature:
-
With
hydrogen;
palladium on activated charcoal;
In
ethanol;
for 16h;
under 3102.89 Torr;
DOI:10.1021/ol048462v
- Guidance literature:
-
Multi-step reaction with 9 steps
1.1: 100 percent / H2 / Pd/C / ethanol / 16 h / 3102.89 Torr
2.1: 94 percent / TiCl4 / CH2Cl2 / 1 h / 0 °C
3.1: 98 percent / BBr3 / CH2Cl2 / 25 h / -78 - 40 °C
4.1: 63 percent / CaCl2*2H2O; KOH / H2O; methanol / 16 h / 0 °C
5.1: 93 percent / p-TsOH / 16 h
6.1: 65 percent / K2CO3 / acetone / 40 h / 57 °C
7.1: 93 percent / aq. HCl / tetrahydrofuran / 72 h / 66 °C
8.1: TiCl4; nBu3N / CH2Cl2 / 4 h / -78 °C
8.2: 50 percent / CH2Cl2 / 2 h / -78 °C
9.1: 74 percent / MnO2 / CH2Cl2 / 4 h
With
hydrogenchloride; manganese(IV) oxide; potassium hydroxide; tributyl-amine; hydrogen; boron tribromide; titanium tetrachloride; potassium carbonate; toluene-4-sulfonic acid; calcium chloride;
palladium on activated charcoal;
In
tetrahydrofuran; methanol; ethanol; dichloromethane; water; acetone;
DOI:10.1021/ol048462v