N-[(9-fluorenyl)methoxycarbonyl]-L-isoleucyl-S-(triphenylmethyl)-L-cysteine tert-butyl ester

Base Information

• Chemical Name: N-[(9-fluorenyl)methoxycarbonyl]-L-isoleucyl-S-(triphenylmethyl)-L-cysteine tert-butyl ester
• CAS No.: 1010440-47-7
• Molecular Formula: C₄₇H₅₀N₂O₅S
• Molecular Weight: 754.99
• Mol file: 1010440-47-7.mol

Synonyms:N-[(9-fluorenyl)methoxycarbonyl]-L-isoleucyl-S-(triphenylmethyl)-L-cysteine tert-butyl ester

Chemical Property of N-[(9-fluorenyl)methoxycarbonyl]-L-isoleucyl-S-(triphenylmethyl)-L-cysteine tert-butyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-[(9-fluorenyl)methoxycarbonyl]-L-isoleucyl-S-(triphenylmethyl)-L-cysteine tert-butyl ester

There total 1 articles about N-[(9-fluorenyl)methoxycarbonyl]-L-isoleucyl-S-(triphenylmethyl)-L-cysteine tert-butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

Fmoc-Ile-OH (71989-23-6,251316-98-0) + S-(triphenylmethyl)-L-cysteine tert-butyl ester (76587-61-6) → N-[(9-fluorenyl)methoxycarbonyl]-L-isoleucyl-S-(triphenylmethyl)-L-cysteine tert-butyl ester (1010440-47-7)

Guidance literature:

With benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; In dichloromethane; at 20 ℃; for 1h; pH=8;

DOI:10.1002/ejoc.200700698

Reference yield: 80.0%

N-[(9-fluorenyl)methoxycarbonyl]-L-isoleucyl-S-(triphenylmethyl)-L-cysteine tert-butyl ester (1010440-47-7) → C32H40N2O3S (1010440-70-6)

Guidance literature:

With piperidine; In dichloromethane; at 20 ℃; for 1h;

DOI:10.1002/ejoc.200700698

upstream raw materials:

Fmoc-Ile-OH

S-(triphenylmethyl)-L-cysteine tert-butyl ester

Downstream raw materials:

C₃₂H₄₀N₂O₃S

Refernces