Chemical Property of Apramycin sulfate
Chemical Property:
- Appearance/Colour:powder
- Vapor Pressure:0mmHg at 25°C
- Melting Point:>168oC (dec.)
- Boiling Point:823 °C at 760 mmHg
- Flash Point:451.6 °C
- PSA：41.99000
- Density:1.56
- LogP:3.82570
- Storage Temp.:2-8°C
- Solubility.:H2O: soluble25mg/mL
- Water Solubility.:Soluble in water.
- Hydrogen Bond Donor Count:13
- Hydrogen Bond Acceptor Count:20
- Rotatable Bond Count:6
- Exact Mass:637.24763686
- Heavy Atom Count:42
- Complexity:841
- Purity/Quality:
-
99% *data from raw suppliers
Apramycin sulfate *data from reagent suppliers
Safty Information:
- Pictogram(s):
T,
Xn
- Hazard Codes:T,Xn
- Statements:
61-35-36/37/38-20/21/22-36/38
- Safety Statements:
53-26-36/37/39-45-36
- MSDS Files:
-
SDS file from LookChem
Useful:
- Canonical SMILES:CNC1C(C2C(CC(C(O2)OC3C(CC(C(C3O)O)N)N)N)OC1OC4C(C(C(C(O4)CO)N)O)O)O.OS(=O)(=O)O
- Isomeric SMILES:CN[C@H]1[C@H]([C@@H]2[C@H](C[C@H]([C@H](O2)O[C@@H]3[C@H](C[C@H]([C@@H]([C@H]3O)O)N)N)N)O[C@@H]1O[C@@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)N)O)O)O.OS(=O)(=O)O
-
Uses
antibacterial; LD50(iv) 280mg/kg(mouse) Apramycin sulfate binds to the deep groove of RNA and effectively inhibits ribosomal translocation prohibiting protein synthesis. Apramycin sulfate is a broad spectrum aminocyclitol antibiotic and component of the Nebramycin complex, produced by a strain of Streptomyces tenebrarius. Antibacterial.
