2,3,6,7-tetramethoxyphenanthro[9,10-b]quinolizidine

Base Information

• Chemical Name: 2,3,6,7-tetramethoxyphenanthro[9,10-b]quinolizidine
• CAS No.: 882738-96-7
• Molecular Formula: C₂₅H₂₉NO₄
• Molecular Weight: 407.51
• Mol file: 882738-96-7.mol

Synonyms:2,3,6,7-tetramethoxyphenanthro[9,10-b]quinolizidine

Chemical Property of 2,3,6,7-tetramethoxyphenanthro[9,10-b]quinolizidine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,3,6,7-tetramethoxyphenanthro[9,10-b]quinolizidine

There total 1 articles about 2,3,6,7-tetramethoxyphenanthro[9,10-b]quinolizidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,3,4,5-tetrahydropyridine (505-18-0) → 2,3,6,7-tetramethoxyphenanthro[9,10-b]quinolizidine (882738-96-7)

Guidance literature:

Multi-step reaction with 4 steps

1: acetic acid / Inert atmosphere

2: N-ethyl-N,N-diisopropylamine / tetrahydrofuran / 20 h / Inert atmosphere; Reflux

3: potassium hexamethylsilazane / tetrahydrofuran / 2.5 h / 0 °C / Inert atmosphere

4: sodium tetrahydroborate / ethanol; tetrahydrofuran / 10 h / 20 °C / Inert atmosphere

With sodium tetrahydroborate; potassium hexamethylsilazane; acetic acid; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; ethanol; 3: |Stevens Rearrangement;

DOI:10.1021/jo400659n

Reference yield: 72.7%

2,3,6,7-tetramethoxyphenanthro[9,10-b]quinolizidine (882738-96-7) + salicylic acid (69-72-7,25496-36-0,8052-31-1) → 2,3,6,7-tetramethoxyphenanthro[9,10-b]quinolizidine salicylate

Guidance literature:

In ethanol; dichloromethane; water; for 6h; Inert atmosphere; Reflux;

Reference yield: 69.0%

2,3,6,7-tetramethoxyphenanthro[9,10-b]quinolizidine (882738-96-7) + toluene-4-sulfonic acid (104-15-4) → 2,3,6,7-tetramethoxyphenanthro[9,10-b]quinolizidine p-toluenesulfonate

Guidance literature:

In ethanol; dichloromethane; water; for 6h; Inert atmosphere; Reflux;

upstream raw materials:

2,3,4,5-tetrahydropyridine