Technology Process of 2R,3R,2-(7-methoxy 1,3-benzodioxol-5-yl) methyl 3-(3,4,5-trimethoxyphenyl) methyl butan-1,4-diol
There total 7 articles about 2R,3R,2-(7-methoxy 1,3-benzodioxol-5-yl) methyl 3-(3,4,5-trimethoxyphenyl) methyl butan-1,4-diol which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
lithium aluminium tetrahydride;
In
tetrahydrofuran;
for 3h;
Ambient temperature;
- Guidance literature:
-
Multi-step reaction with 4 steps
2: 94 percent / calcium borohydride
3: 1.) LiN(SiMe3)2 / 1.) THF/hexane, -50 deg C, 1 h, 2.) THF, -78 deg C, 30 min.
4: 90 percent / LiAlH4 / tetrahydrofuran / 3 h / Ambient temperature
With
lithium aluminium tetrahydride; calcium borohydride; lithium hexamethyldisilazane;
In
tetrahydrofuran;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 99 percent / sodium borohydride / methanol; CH2Cl2
2: 70 percent / PBr3 / ethyl acetate / 1 h / 20 °C
3: 1.) LiN(SiMe3)2 / 1.) THF/hexane, -50 deg C, 1 h, 2.) THF, -78 deg C, 30 min.
4: 90 percent / LiAlH4 / tetrahydrofuran / 3 h / Ambient temperature
With
sodium tetrahydroborate; lithium aluminium tetrahydride; phosphorus tribromide; lithium hexamethyldisilazane;
In
tetrahydrofuran; methanol; dichloromethane; ethyl acetate;
