Citalopram hydrobromide

Base Information

Chemical Name:Citalopram hydrobromide
CAS No.:59729-32-7
Molecular Formula:C20H22BrFN2O
Molecular Weight:405.31
Hs Code.:29329990
European Community (EC) Number:261-890-6
NSC Number:758684
UNII:I1E9D14F36
DSSTox Substance ID:DTXSID40872344
Wikidata:Q27280253
NCI Thesaurus Code:C28932
RXCUI:221078
Pharos Ligand ID:G1J69NL9LH2V
ChEMBL ID:CHEMBL1200781
Mol file:59729-32-7.mol

Synonyms:Celexa;Citalopram;Citalopram Hydrobromide;Cytalopram;Lu-10-171;Lu10171;Seropram

Suppliers and Price of Citalopram hydrobromide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Citalopram hydrobromide
10mg
$ 409.00

TRC
Citalopram,HydrobromideSalt
25g
$ 825.00

TRC
Citalopram,HydrobromideSalt
1g
$ 165.00

Tocris
Citalopram Hydrobromide ≥99%(HPLC)
10
$ 147.00

Tocris
Citalopram Hydrobromide ≥99%(HPLC)
50
$ 616.00

TCI Chemical
Citalopram Hydrobromide >98.0%(HPLC)(T)
5g
$ 318.00

TCI Chemical
Citalopram Hydrobromide >98.0%(HPLC)(T)
1g
$ 93.00

Sigma-Aldrich
Citalopram hydrobromide solution
057-1ml
$ 55.00

Sigma-Aldrich
Citalopram hydrobromide solution 100?μg/mL in methanol (as free base), ampule of 1?mL, certified reference material, Cerilliant?
1 mL
$ 56.80

Sigma-Aldrich
Citalopram Hydrobromide Pharmaceutical Secondary Standard; Certified Reference Material
1g
$ 114.00

Total 207 raw suppliers

Chemical Property of Citalopram hydrobromide

Chemical Property:

Appearance/Colour:White Crystalline Powder
Vapor Pressure:1.53E-07mmHg at 25°C
Melting Point:182-188°C
Boiling Point:428.3 °C at 760 mmHg
Flash Point:212.8 °C
PSA：36.26000
LogP:4.77108
Storage Temp.:-20°C Freezer
Solubility.:H2O: soluble (sparingly)
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:404.08995
Heavy Atom Count:25
Complexity:466

Purity/Quality:

99%, ^*data from raw suppliers

Citalopram hydrobromide ^*data from reagent suppliers

Safty Information:

Pictogram(s): F,T
Hazard Codes:F,T
Statements: 11-23/24/25-39/23/24/25-22
Safety Statements: 7-16-36/37-45-24/25

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN(C)CCCC1(C2=C(CO1)C=C(C=C2)C#N)C3=CC=C(C=C3)F.Br
Recent ClinicalTrials:A Trial to Evaluate the Efficacy, Safety & Tolerability of Brexpiprazole in the Maintenance Treatment of Adults With Major Depressive Disorder
Recent EU Clinical Trials:Prefrontal circuits for cognitive flexibility in an extradimensional set-shifting task for humans.
Description Citalopram (hydrobromide) (Item No. 23252) is an analytical reference material categorized as an antidepressant. This product is intended for use in analytical forensic applications. This product is also available as a general research tool .
Uses An inhibitor of serotonin (5-HT) uptake. Used as an antidepressant Antidepressant;5HT uptake inhibitor Anti-depressant/Anti-psychotic Citalopram hydrobromide has been used:to examine its effects on?sirt?mRNA and mammalian sirtuins (SIRT) expression in miceto monitor body temperature and antidepressant-like behavioral responses in the forced swim test for ratsfor 5-hydroxytryptamine (5-HT) competition uptake assays
Therapeutic Function Antidepressant

Technology Process of Citalopram hydrobromide

There total 14 articles about Citalopram hydrobromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.6%

: 59729-33-8
1-(3-dimethylamino-propyl)-1-(4-fluoro-phenyl)-1,3-dihydro-isobenzofuran-5-carbonitrile

: 59729-32-7
citalopram hydrobromide

Guidance literature:: With hydrogen bromide; In water; toluene; at 5 - 10 ℃; Heating / reflux;

Reference yield: 90.0%

: 59729-32-7
citalopram hydrobromide

Guidance literature:

Reference yield: 65.0%

: 265137-39-1
4,4-dimethyl-2-[1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-yl]oxazoline

: 59729-32-7
citalopram hydrobromide

Guidance literature:: 4,4-dimethyl-2-[1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-yl]oxazoline; With trichlorophosphate; In pyridine; at 5 - 115 ℃; for 3 - 4h;

With ammonia; In water; at 10 ℃; pH=9;

With hydrogen bromide; In acetone; at 10 ℃; pH=4 - 5;