N-methoxy-2-(N-(4-methoxyphenyl)-4-methylphenylsulfonamido)-N-methylacetamide

Base Information

• Chemical Name: N-methoxy-2-(N-(4-methoxyphenyl)-4-methylphenylsulfonamido)-N-methylacetamide
• CAS No.: 1444623-83-9
• Molecular Formula: C₁₈H₂₂N₂O₅S
• Molecular Weight: 378.449
• Mol file: 1444623-83-9.mol

Synonyms:N-methoxy-2-(N-(4-methoxyphenyl)-4-methylphenylsulfonamido)-N-methylacetamide

Chemical Property of N-methoxy-2-(N-(4-methoxyphenyl)-4-methylphenylsulfonamido)-N-methylacetamide

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of N-methoxy-2-(N-(4-methoxyphenyl)-4-methylphenylsulfonamido)-N-methylacetamide

There total 1 articles about N-methoxy-2-(N-(4-methoxyphenyl)-4-methylphenylsulfonamido)-N-methylacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

2-iodo-N-methoxy-N-methylacetamide (163089-33-6) + N-(4-Methoxy-phenyl)-4-methyl-benzenesulfonamide (1150-26-1) → N-methoxy-2-(N-(4-methoxyphenyl)-4-methylphenylsulfonamido)-N-methylacetamide (1444623-83-9)

Guidance literature:

With potassium carbonate; In acetonitrile; for 12h; Reflux;

DOI:10.1002/adsc.201201043

Reference yield: 92.0%

Chloroiodomethane (593-71-5) + N-methoxy-2-(N-(4-methoxyphenyl)-4-methylphenylsulfonamido)-N-methylacetamide (1444623-83-9) → N-(3-chloro-2-oxopropyl)-N-(4-methoxyphenyl)-4-methylbenzenesulfonamide (1444623-67-9)

Guidance literature:

With methyllithium lithium bromide; In tetrahydrofuran; diethyl ether; nitrogen; at -90 ℃; for 1h; liquid N₂;

DOI:10.1002/adsc.201201043

upstream raw materials:

2-iodo-N-methoxy-N-methylacetamide

N-(4-Methoxy-phenyl)-4-methyl-benzenesulfonamide

Downstream raw materials:

N-(3-chloro-2-oxopropyl)-N-(4-methoxyphenyl)-4-methylbenzenesulfonamide