(3'aS,4'R,5'R,7'aR)-7-Ethoxymethoxy-2',2'-dimethyl-4'-(toluene-4-sulfonylamino)-3'a,4',5',7'a-tetrahydro-[5,5']bi[benzo[1,3]dioxolyl]-6-carboxylic acid diethylamide

Base Information

Chemical Name:(3'aS,4'R,5'R,7'aR)-7-Ethoxymethoxy-2',2'-dimethyl-4'-(toluene-4-sulfonylamino)-3'a,4',5',7'a-tetrahydro-[5,5']bi[benzo[1,3]dioxolyl]-6-carboxylic acid diethylamide
CAS No.:163082-18-6
Molecular Formula:C₃₁H₄₀N₂O₉S
Molecular Weight:616.733
Hs Code.:

(3'aS,4'R,5'R,7'aR)-7-Ethoxymethoxy-2',2'-dimethyl-4'-(toluene-4-sulfonylamino)-3'a,4',5',7'a-tetrahydro-[5,5']bi[benzo[1,3]dioxolyl]-6-carboxylic acid diethylamide

Synonyms:(3'aS,4'R,5'R,7'aR)-7-Ethoxymethoxy-2',2'-dimethyl-4'-(toluene-4-sulfonylamino)-3'a,4',5',7'a-tetrahydro-[5,5']bi[benzo[1,3]dioxolyl]-6-carboxylic acid diethylamide

Suppliers and Price of (3'aS,4'R,5'R,7'aR)-7-Ethoxymethoxy-2',2'-dimethyl-4'-(toluene-4-sulfonylamino)-3'a,4',5',7'a-tetrahydro-[5,5']bi[benzo[1,3]dioxolyl]-6-carboxylic acid diethylamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (3'aS,4'R,5'R,7'aR)-7-Ethoxymethoxy-2',2'-dimethyl-4'-(toluene-4-sulfonylamino)-3'a,4',5',7'a-tetrahydro-[5,5']bi[benzo[1,3]dioxolyl]-6-carboxylic acid diethylamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (3'aS,4'R,5'R,7'aR)-7-Ethoxymethoxy-2',2'-dimethyl-4'-(toluene-4-sulfonylamino)-3'a,4',5',7'a-tetrahydro-[5,5']bi[benzo[1,3]dioxolyl]-6-carboxylic acid diethylamide

There total 10 articles about (3'aS,4'R,5'R,7'aR)-7-Ethoxymethoxy-2',2'-dimethyl-4'-(toluene-4-sulfonylamino)-3'a,4',5',7'a-tetrahydro-[5,5']bi[benzo[1,3]dioxolyl]-6-carboxylic acid diethylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 67451-62-1,82683-92-9,132958-32-8,130792-45-9
cis-(1S,2S)-1,2-dihydroxy-3-bromocyclohexa-3,5-diene

: 163082-18-6
(3'aS,4'R,5'R,7'aR)-7-Ethoxymethoxy-2',2'-dimethyl-4'-(toluene-4-sulfonylamino)-3'a,4',5',7'a-tetrahydro-[5,5']bi[benzo[1,3]dioxolyl]-6-carboxylic acid diethylamide

Guidance literature:: Multi-step reaction with 4 steps

1: p-TsOH*H₂O / acetone / 0.33 h / Ambient temperature

2: 54 percent / Cu(acac)2 / acetonitrile / 1 h / Ambient temperature

3: 78 percent / Bu₃SnH, AIBN / tetrahydrofuran / 2 h / Heating

4: 1.) s-BuLi, TMEDA, 2.) CuCN, 3.) BF₃*Et₂O

With copper acetylacetonate; 2,2'-azobis(isobutyronitrile); N,N,N,N,-tetramethylethylenediamine; boron trifluoride diethyl etherate; sec.-butyllithium; tri-n-butyl-tin hydride; toluene-4-sulfonic acid; In tetrahydrofuran; acetone; acetonitrile;
DOI:10.1021/ja960596j

Reference yield:

: 130669-75-9
(3aS,7aS)-4-bromo-2,2-dimethyl-3a,7a-dihydro-1,3-benzodioxole

: 163082-18-6
(3'aS,4'R,5'R,7'aR)-7-Ethoxymethoxy-2',2'-dimethyl-4'-(toluene-4-sulfonylamino)-3'a,4',5',7'a-tetrahydro-[5,5']bi[benzo[1,3]dioxolyl]-6-carboxylic acid diethylamide

Guidance literature:: Multi-step reaction with 3 steps

1: 54 percent / Cu(acac)2 / acetonitrile / 1 h / Ambient temperature

2: 78 percent / Bu₃SnH, AIBN / tetrahydrofuran / 2 h / Heating

3: 1.) s-BuLi, TMEDA, 2.) CuCN, 3.) BF₃*Et₂O

With copper acetylacetonate; 2,2'-azobis(isobutyronitrile); N,N,N,N,-tetramethylethylenediamine; boron trifluoride diethyl etherate; sec.-butyllithium; tri-n-butyl-tin hydride; In tetrahydrofuran; acetonitrile;
DOI:10.1021/ja960596j

Reference yield:

: 163082-04-0
(1R,4S,5S,6R)-3-bromo-4,5-(isopropylidenedioxy)-7-(4'-methylphenylsulfonyl)-7-azabicyclo<4.1.0>hept-2-ene

: 163082-18-6
(3'aS,4'R,5'R,7'aR)-7-Ethoxymethoxy-2',2'-dimethyl-4'-(toluene-4-sulfonylamino)-3'a,4',5',7'a-tetrahydro-[5,5']bi[benzo[1,3]dioxolyl]-6-carboxylic acid diethylamide

Guidance literature:: Multi-step reaction with 2 steps

1: 78 percent / Bu₃SnH, AIBN / tetrahydrofuran / 2 h / Heating

2: 1.) s-BuLi, TMEDA, 2.) CuCN, 3.) BF₃*Et₂O

With 2,2'-azobis(isobutyronitrile); N,N,N,N,-tetramethylethylenediamine; boron trifluoride diethyl etherate; sec.-butyllithium; tri-n-butyl-tin hydride; In tetrahydrofuran;
DOI:10.1021/ja960596j