(1S,2R,3S,4S,6S)-4-(acetoxymethyl)-4-hydroxy-6-(4-phenyl-1H-1,2,3-triazol-1-yl)cyclohexane-1,2,3-triyl triacetate

Base Information

Chemical Name:(1S,2R,3S,4S,6S)-4-(acetoxymethyl)-4-hydroxy-6-(4-phenyl-1H-1,2,3-triazol-1-yl)cyclohexane-1,2,3-triyl triacetate
CAS No.:1618636-16-0
Molecular Formula:C₂₃H₂₇N₃O₉
Molecular Weight:489.482
Hs Code.:

Synonyms:(1S,2R,3S,4S,6S)-4-(acetoxymethyl)-4-hydroxy-6-(4-phenyl-1H-1,2,3-triazol-1-yl)cyclohexane-1,2,3-triyl triacetate

Suppliers and Price of (1S,2R,3S,4S,6S)-4-(acetoxymethyl)-4-hydroxy-6-(4-phenyl-1H-1,2,3-triazol-1-yl)cyclohexane-1,2,3-triyl triacetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (1S,2R,3S,4S,6S)-4-(acetoxymethyl)-4-hydroxy-6-(4-phenyl-1H-1,2,3-triazol-1-yl)cyclohexane-1,2,3-triyl triacetate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (1S,2R,3S,4S,6S)-4-(acetoxymethyl)-4-hydroxy-6-(4-phenyl-1H-1,2,3-triazol-1-yl)cyclohexane-1,2,3-triyl triacetate

There total 4 articles about (1S,2R,3S,4S,6S)-4-(acetoxymethyl)-4-hydroxy-6-(4-phenyl-1H-1,2,3-triazol-1-yl)cyclohexane-1,2,3-triyl triacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 148347-73-3
(1S,2R,3S,4S,6S)-4-(acetoxymethyl)-6-azido-4-hydroxycyclohexane-1,2,3-triyl triacetate

: 536-74-3
phenylacetylene

: 1618636-16-0
(1S,2R,3S,4S,6S)-4-(acetoxymethyl)-4-hydroxy-6-(4-phenyl-1H-1,2,3-triazol-1-yl)cyclohexane-1,2,3-triyl triacetate

Guidance literature:: With copper(l) iodide; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 100 ℃; for 6h; Inert atmosphere;
DOI:10.1002/ejoc.201301874

Reference yield:

: 83465-22-9
(1S,2S,3R,4S,5S)-1-amino-5-hydroxymethyl-2,3,4,5-tetrahydroxycyclohexane

: 1618636-16-0
(1S,2R,3S,4S,6S)-4-(acetoxymethyl)-4-hydroxy-6-(4-phenyl-1H-1,2,3-triazol-1-yl)cyclohexane-1,2,3-triyl triacetate

Guidance literature:: Multi-step reaction with 3 steps

1: imidazole-1-sulfonyl azide hydrochloride; potassium carbonate; copper(ll) sulfate pentahydrate / methanol / 12 h / 20 °C

2: sodium L-ascorbate / N,N-dimethyl-formamide / 8 h / 100 °C / Inert atmosphere

3: dmap / N,N-dimethyl-formamide / 6 h / Inert atmosphere

With dmap; imidazole-1-sulfonyl azide hydrochloride; copper(ll) sulfate pentahydrate; potassium carbonate; sodium L-ascorbate; In methanol; N,N-dimethyl-formamide;
DOI:10.1002/ejoc.201301874

Reference yield:

: 1054636-37-1
(1S,2S,3R,4S,5S)-1-azido-5-hydroxymethyl-2,3,4,5-tetrahydroxycyclohexane

: 1618636-16-0
(1S,2R,3S,4S,6S)-4-(acetoxymethyl)-4-hydroxy-6-(4-phenyl-1H-1,2,3-triazol-1-yl)cyclohexane-1,2,3-triyl triacetate

Guidance literature:: Multi-step reaction with 2 steps

1: pyridine; dichloromethane / 8 h / 20 °C

2: copper(l) iodide; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 6 h / 100 °C / Inert atmosphere

With copper(l) iodide; N-ethyl-N,N-diisopropylamine; In pyridine; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1002/ejoc.201301874