1-[p-(N,N-diethylamino)phenyl]-4(S)-hydroxy-2-amino-5(S)-[N-(N-methoxycarbonyl-(L)-tert-leucyl)amino]-6-phenyl-2-azahexane hydrochloride

Base Information

• Chemical Name: 1-[p-(N,N-diethylamino)phenyl]-4(S)-hydroxy-2-amino-5(S)-[N-(N-methoxycarbonyl-(L)-tert-leucyl)amino]-6-phenyl-2-azahexane hydrochloride
• CAS No.: 202586-22-9
• Molecular Formula: C₂₉H₄₅N₅O₄*ClH
• Molecular Weight: 564.168

Synonyms:1-[p-(N,N-diethylamino)phenyl]-4(S)-hydroxy-2-amino-5(S)-[N-(N-methoxycarbonyl-(L)-tert-leucyl)amino]-6-phenyl-2-azahexane hydrochloride

Chemical Property of 1-[p-(N,N-diethylamino)phenyl]-4(S)-hydroxy-2-amino-5(S)-[N-(N-methoxycarbonyl-(L)-tert-leucyl)amino]-6-phenyl-2-azahexane hydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

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Useful:

Technology Process of 1-[p-(N,N-diethylamino)phenyl]-4(S)-hydroxy-2-amino-5(S)-[N-(N-methoxycarbonyl-(L)-tert-leucyl)amino]-6-phenyl-2-azahexane hydrochloride

There total 1 articles about 1-[p-(N,N-diethylamino)phenyl]-4(S)-hydroxy-2-amino-5(S)-[N-(N-methoxycarbonyl-(L)-tert-leucyl)amino]-6-phenyl-2-azahexane hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-[p-(N,N-Diethylamino)phenyl]-4(S)-hydroxy-2-(tert-butyloxycarbonyl)amino-5(S)-[N-(N-methoxycarbonyl-(L)-tertleucyl)amino]-6-phenyl-2-azahexane (202586-21-8) → 1-[p-(N,N-diethylamino)phenyl]-4(S)-hydroxy-2-amino-5(S)-[N-(N-methoxycarbonyl-(L)-tert-leucyl)amino]-6-phenyl-2-azahexane hydrochloride (202586-22-9)

Guidance literature:

With hydrogenchloride; In 1,4-dioxane; N,N-dimethyl-formamide; toluene;

Reference yield:

N-methoxycarbonyl-(L)-tert-leucine + 1-[p-(N,N-diethylamino)phenyl]-4(S)-hydroxy-2-amino-5(S)-[N-(N-methoxycarbonyl-(L)-tert-leucyl)amino]-6-phenyl-2-azahexane hydrochloride (202586-22-9) → 1-[p-(N,N-Diethylamino)phenyl]-4(S)-hydroxy-5(S)-2,5-bis[N-(N-methoxycarbonyl-(L)-tert-leucyl)amino]-6-phenyl-2-azahexane (202586-00-3)

Guidance literature:

In dichloromethane; water; N,N-dimethyl-formamide;

Reference yield:

1-[p-(N,N-diethylamino)phenyl]-4(S)-hydroxy-2-amino-5(S)-[N-(N-methoxycarbonyl-(L)-tert-leucyl)amino]-6-phenyl-2-azahexane hydrochloride (202586-22-9) + N-methoxycarbonyl-L-valine (111398-44-8,74761-42-5) → 1-[p-(N,N-diethylamino)phenyl]-4(S)-hydroxy-2-[N-(N-methoxycarbonyl-(L)-valyl)amino]-5(S)-[N-(N-methoxycarbonyl-(L)-tert-leucyl)amino]-6-phenyl-2-azahexane (202586-01-4)

Guidance literature:

In N,N-dimethyl-formamide;

upstream raw materials:

1-[p-(N,N-Diethylamino)phenyl]-4(S)-hydroxy-2-(tert-butyloxycarbonyl)amino-5(S)-[N-(N-methoxycarbonyl-(L)-tertleucyl)amino]-6-phenyl-2-azahexane

Downstream raw materials:

1-[p-(N,N-Diethylamino)phenyl]-4(S)-hydroxy-5(S)-2,5-bis[N-(N-methoxycarbonyl-(L)-tert-leucyl)amino]-6-phenyl-2-azahexane

1-[p-(N,N-diethylamino)phenyl]-4(S)-hydroxy-2-[N-(N-methoxycarbonyl-(L)-valyl)amino]-5(S)-[N-(N-methoxycarbonyl-(L)-tert-leucyl)amino]-6-phenyl-2-azahexane

1-[p-(N,N-diethylamino)phenyl]-4(S)-hydroxy-2-[N-(N-methoxycarbonyl-(L)-isoleucyl)amino]-5(S)-[N-(N-methoxycarbonyl-(L)-tert-leucyl)amino]-6-phenyl-2-azahexane

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