(1RS)-(+/-)-1-benzyl-2-tert-butyl-prop-2-enyl 2-(diphenylphosphanyl)benzoate

Base Information

• Chemical Name: (1RS)-(+/-)-1-benzyl-2-tert-butyl-prop-2-enyl 2-(diphenylphosphanyl)benzoate
• CAS No.: 536696-57-8
• Molecular Formula: C₃₃H₃₃O₂P
• Molecular Weight: 492.598
• Mol file: 536696-57-8.mol

Synonyms:(1RS)-(+/-)-1-benzyl-2-tert-butyl-prop-2-enyl 2-(diphenylphosphanyl)benzoate

Chemical Property of (1RS)-(+/-)-1-benzyl-2-tert-butyl-prop-2-enyl 2-(diphenylphosphanyl)benzoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (1RS)-(+/-)-1-benzyl-2-tert-butyl-prop-2-enyl 2-(diphenylphosphanyl)benzoate

There total 3 articles about (1RS)-(+/-)-1-benzyl-2-tert-butyl-prop-2-enyl 2-(diphenylphosphanyl)benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

ortho-diphenylphosphinobenzoic acid (17261-28-8) + 3-tert-butyl-1-phenyl-but-3-en-2-ol (536696-52-3) → (1RS)-(+/-)-1-benzyl-2-tert-butyl-prop-2-enyl 2-(diphenylphosphanyl)benzoate (536696-57-8)

Guidance literature:

With dmap; dicyclohexyl-carbodiimide; In dichloromethane; at 20 ℃;

DOI:10.1002/chem.200390044

Reference yield:

3,3-dimethylbutyrylaldehyde (2987-16-8) → (1RS)-(+/-)-1-benzyl-2-tert-butyl-prop-2-enyl 2-(diphenylphosphanyl)benzoate (536696-57-8)

Guidance literature:

Multi-step reaction with 3 steps

1.1: 40 percent / aq. Me₂NH*HCl; NaHCO₃ / pH 7

2.1: Mg / diethyl ether

2.2: 59 percent / diethyl ether / 20 °C

3.1: 84 percent / DMAP; DCC / CH₂Cl₂ / 20 °C

With dmap; N,N-dimethylammonium chloride; sodium hydrogencarbonate; magnesium; dicyclohexyl-carbodiimide; In diethyl ether; dichloromethane; 1.1: Mannich reaction;

DOI:10.1002/chem.200390044

Reference yield:

3,3-dimethyl-2-methylenebutanal (69060-18-0) → (1RS)-(+/-)-1-benzyl-2-tert-butyl-prop-2-enyl 2-(diphenylphosphanyl)benzoate (536696-57-8)

Guidance literature:

Multi-step reaction with 2 steps

1.1: Mg / diethyl ether

1.2: 59 percent / diethyl ether / 20 °C

2.1: 84 percent / DMAP; DCC / CH₂Cl₂ / 20 °C

With dmap; magnesium; dicyclohexyl-carbodiimide; In diethyl ether; dichloromethane;

DOI:10.1002/chem.200390044

upstream raw materials:

ortho-diphenylphosphinobenzoic acid

3-tert-butyl-1-phenyl-but-3-en-2-ol

3,3-dimethylbutyrylaldehyde

3,3-dimethyl-2-methylenebutanal