Acriflavine

Base Information

• Chemical Name: Acriflavine
• CAS No.: 8048-52-0
• Deprecated CAS: 51555-26-1,53307-10-1,8048-52-0,8018-07-3,8063-24-9,50922-89-9,51367-34-1
• Molecular Formula: C27H25ClN6
• Molecular Weight: 468.98
• Hs Code.: 38249064
• European Community (EC) Number: 623-012-3,933-379-4,938-197-9
• DSSTox Substance ID: DTXSID30988185
• Wikipedia: Euflavine,Acriflavine
• NCI Thesaurus Code: C76253
• ChEMBL ID: CHEMBL2360628
• Mol file: 8048-52-0.mol

Synonyms:2,8-Diamino-10-Methylacridinium Chloride Mixture With 2,8-Diaminoacridine;Acriflavine;Xanthacridinum

Chemical Property of Acriflavine

Chemical Property:

• Appearance/Colour: Deep orange to brownish-red powder
• Melting Point: 179-181 °C
• Refractive Index: 1.6000 (estimate)
• Boiling Point: 612.69°C (rough estimate)
• PSA: 120.85000
• Density: 1.0933 (rough estimate)
• LogP: 3.86310
• Solubility.: H2O: soluble0.33g/mL (lit.)(lit.)
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 0
• Exact Mass: 468.1829225
• Heavy Atom Count: 34
• Complexity: 486

Purity/Quality:

99% ^*data from raw suppliers

Acriflavine (mixture of 3,6-Diamino-10-methylacridinium Chloride and 3,6-Diaminoacridine) >70.0%(HPLC) ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn,N
• Hazard Codes: Xn,N
• Statements: 22-37/38-41-50/53-20/21/22-50-36/37/38
• Safety Statements: 26-39-60-61-36-37/39-29-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

• Chemical Classes: Dyes -> Acridine Dyes
• Canonical SMILES: C[N+]1=C2C=C(C=CC2=CC3=C1C=C(C=C3)N)N.C1=CC(=CC2=NC3=C(C=CC(=C3)N)C=C21)N.[Cl-]
• Recent ClinicalTrials: Clinical Assessment of Urinary Antiseptics Methenamine and Methylthioninium in Recurrent Cystitis
• Uses: Acriflavine is used in applications for dual fluorescence analysis of cellular DNA and protein simultaneously. Fluorescent label for high molecular weight RNA