(+/-)-2-<(3RS,4SR)-N-benzyloxycarbonyl-3-ethyl-4-piperidylethyl>-3-ethoxycarbonylmethylindole

Base Information

Chemical Name:(+/-)-2-<(3RS,4SR)-N-benzyloxycarbonyl-3-ethyl-4-piperidylethyl>-3-ethoxycarbonylmethylindole
CAS No.:104777-76-6
Molecular Formula:C₂₉H₃₆N₂O₄
Molecular Weight:476.616
Hs Code.:

Synonyms:(+/-)-2-<(3RS,4SR)-N-benzyloxycarbonyl-3-ethyl-4-piperidylethyl>-3-ethoxycarbonylmethylindole

Suppliers and Price of (+/-)-2-<(3RS,4SR)-N-benzyloxycarbonyl-3-ethyl-4-piperidylethyl>-3-ethoxycarbonylmethylindole

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (+/-)-2-<(3RS,4SR)-N-benzyloxycarbonyl-3-ethyl-4-piperidylethyl>-3-ethoxycarbonylmethylindole

Chemical Property:

Purity/Quality:

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Technology Process of (+/-)-2-<(3RS,4SR)-N-benzyloxycarbonyl-3-ethyl-4-piperidylethyl>-3-ethoxycarbonylmethylindole

There total 9 articles about (+/-)-2-<(3RS,4SR)-N-benzyloxycarbonyl-3-ethyl-4-piperidylethyl>-3-ethoxycarbonylmethylindole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: (3R,4S)-4-[(E)-2-(3-Ethoxycarbonylmethyl-1H-indol-2-yl)-vinyl]-3-ethyl-piperidine-1-carboxylic acid benzyl ester

: 104777-76-6
(+/-)-2-<(3RS,4SR)-N-benzyloxycarbonyl-3-ethyl-4-piperidylethyl>-3-ethoxycarbonylmethylindole

Guidance literature:: With hydrogen; platinum(IV) oxide; In ethanol; for 2h; Yield given; Ambient temperature;

Reference yield:

: (+/-)-N-benzyloxycarbonyl-3-ethyl-4-piperidone

: 104777-76-6
(+/-)-2-<(3RS,4SR)-N-benzyloxycarbonyl-3-ethyl-4-piperidylethyl>-3-ethoxycarbonylmethylindole

Guidance literature:: Multi-step reaction with 8 steps

1: NaH

2: H₂ / PtO₂

3: LiOH / methanol; H₂O

4: (COCl)2 / CH₂Cl₂

5: SnCl₄ / diethyl ether / 0.17 h / 0 °C

6: NaBH₄

7: AcOH / benzene / Heating

8: H₂ / PtO₂

With lithium hydroxide; sodium tetrahydroborate; oxalyl dichloride; hydrogen; tin(IV) chloride; sodium hydride; acetic acid; platinum(IV) oxide; In methanol; diethyl ether; dichloromethane; water; benzene;
DOI:10.1039/c39860000573

Reference yield:

: 501-53-1,94274-21-2
benzyl chloroformate

: 104777-76-6
(+/-)-2-<(3RS,4SR)-N-benzyloxycarbonyl-3-ethyl-4-piperidylethyl>-3-ethoxycarbonylmethylindole

Guidance literature:: Multi-step reaction with 9 steps

1: NaHCO₃

2: NaH

3: H₂ / PtO₂

4: LiOH / methanol; H₂O

5: (COCl)2 / CH₂Cl₂

6: SnCl₄ / diethyl ether / 0.17 h / 0 °C

7: NaBH₄

8: AcOH / benzene / Heating

9: H₂ / PtO₂

With lithium hydroxide; sodium tetrahydroborate; oxalyl dichloride; hydrogen; tin(IV) chloride; sodium hydride; sodium hydrogencarbonate; acetic acid; platinum(IV) oxide; In methanol; diethyl ether; dichloromethane; water; benzene;
DOI:10.1039/c39860000573