9H-fluoren-9-ylmethyl N-(1-{[4-({2-[2-(2-{[(tert-butoxy)carbonyl]amino}ethoxy)ethoxy]ethyl}carbamoyl)phenyl]methyl}piperidin-4-yl)carbamate

Base Information

Chemical Name:9H-fluoren-9-ylmethyl N-(1-{[4-({2-[2-(2-{[(tert-butoxy)carbonyl]amino}ethoxy)ethoxy]ethyl}carbamoyl)phenyl]methyl}piperidin-4-yl)carbamate
CAS No.:1444124-11-1
Molecular Formula:C₃₉H₅₀N₄O₇
Molecular Weight:686.849
Hs Code.:

Synonyms:9H-fluoren-9-ylmethyl N-(1-{[4-({2-[2-(2-{[(tert-butoxy)carbonyl]amino}ethoxy)ethoxy]ethyl}carbamoyl)phenyl]methyl}piperidin-4-yl)carbamate

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Chemical Property of 9H-fluoren-9-ylmethyl N-(1-{[4-({2-[2-(2-{[(tert-butoxy)carbonyl]amino}ethoxy)ethoxy]ethyl}carbamoyl)phenyl]methyl}piperidin-4-yl)carbamate

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Technology Process of 9H-fluoren-9-ylmethyl N-(1-{[4-({2-[2-(2-{[(tert-butoxy)carbonyl]amino}ethoxy)ethoxy]ethyl}carbamoyl)phenyl]methyl}piperidin-4-yl)carbamate

There total 1 articles about 9H-fluoren-9-ylmethyl N-(1-{[4-({2-[2-(2-{[(tert-butoxy)carbonyl]amino}ethoxy)ethoxy]ethyl}carbamoyl)phenyl]methyl}piperidin-4-yl)carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 13.0%

: 1444124-37-1
4-[(4-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}piperidin-1-yl)methyl]benzoic acid

: 153086-78-3
tert-butyl {2-[2-(2-aminoethoxy)ethoxy]ethyl}carbamate

: 1444124-11-1
9H-fluoren-9-ylmethyl N-(1-{[4-({2-[2-(2-{[(tert-butoxy)carbonyl]amino}ethoxy)ethoxy]ethyl}carbamoyl)phenyl]methyl}piperidin-4-yl)carbamate

Guidance literature:: 4-[(4-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}piperidin-1-yl)methyl]benzoic acid; With O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; for 0.0833333h;

tert-butyl {2-[2-(2-aminoethoxy)ethoxy]ethyl}carbamate; In N,N-dimethyl-formamide;

Reference yield: 37.0%

: 1444124-11-1
9H-fluoren-9-ylmethyl N-(1-{[4-({2-[2-(2-{[(tert-butoxy)carbonyl]amino}ethoxy)ethoxy]ethyl}carbamoyl)phenyl]methyl}piperidin-4-yl)carbamate

: tert-butyl N-(2-{2-[2-({4-[(4-aminopiperidin-1-yl)methyl]phenyl}formamido)ethoxy]ethoxy}ethyl)carbamate difluoroacetic acid salt

Guidance literature:: 9H-fluoren-9-ylmethyl N-(1-{[4-({2-[2-(2-{[(tert-butoxy)carbonyl]amino}ethoxy)ethoxy]ethyl}carbamoyl)phenyl]methyl}piperidin-4-yl)carbamate; With piperidine; In tetrahydrofuran;

With trifluoroacetic acid;

Reference yield: 37.0%

: 1444124-11-1
9H-fluoren-9-ylmethyl N-(1-{[4-({2-[2-(2-{[(tert-butoxy)carbonyl]amino}ethoxy)ethoxy]ethyl}carbamoyl)phenyl]methyl}piperidin-4-yl)carbamate

: 76-05-1
trifluoroacetic acid

: tert-butyl N-(2-{2-[2-({4-[(4-aminopiperidin-1-yl)methyl]phenyl}formamido)ethoxy]ethoxy}ethyl)carbamate difluoroacetic acid salt

Guidance literature:: 9H-fluoren-9-ylmethyl N-(1-{[4-({2-[2-(2-{[(tert-butoxy)carbonyl]amino}ethoxy)ethoxy]ethyl}carbamoyl)phenyl]methyl}piperidin-4-yl)carbamate; With piperidine; In tetrahydrofuran;

trifluoroacetic acid;