Basic red 2

Base Information

• Chemical Name: Basic red 2
• CAS No.: 477-73-6
• Deprecated CAS: 74109-45-8
• Molecular Formula: C20H19ClN4
• Molecular Weight: 350.851
• Hs Code.: 32041300
• European Community (EC) Number: 207-518-8,807-152-4
• NSC Number: 47719
• UNII: XTX0YXU2HV
• DSSTox Substance ID: DTXSID60874047
• Wikipedia: Safranin
• Wikidata: Q413672
• ChEMBL ID: CHEMBL5195997
• Mol file: 477-73-6.mol

Synonyms:Basic Red 2;safranin;safranin O;safranine;Safranine O;safranine T

Chemical Property of Basic red 2

Chemical Property:

• Appearance/Colour: Dark red to violet powder
• Melting Point: >240℃ (decompose)
• Refractive Index: n20/D 1.339
• Boiling Point: 507.14°C (rough estimate)
• PKA: 6.4(at 25℃)
• Flash Point: 46 °C
• PSA: 68.81000
• Density: 1.00 g/mL at 20 °C
• LogP: 1.61230
• Storage Temp.: Store at RT.
• Solubility.: H2O: soluble1mg/mL
• Water Solubility.: soluble
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 1
• Exact Mass: 350.1298243
• Heavy Atom Count: 25
• Complexity: 405

Purity/Quality:

98% ^*data from raw suppliers

Safranine O, Certified ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 41-36/38-37/38-10-36/37/38
• Safety Statements: 26-39-24/25-36-16

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Dyes -> Azine Dyes
• Canonical SMILES: CC1=CC2=C(C=C1N)[N+](=C3C=C(C(=CC3=N2)C)N)C4=CC=CC=C4.[Cl-]
• Uses: A biological stain used to stain Gram negative bacteria, chromosomes, mucin, cartilage and mast cells. Dyes and metabolites, Environmental Testing In forensics to visualize details of cyanoacrylate-fumed friction ridges of human digits.

Technology Process of Basic red 2

There total 4 articles about Basic red 2 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

o-toluidine (95-53-4) → safranin O (477-73-6,74109-45-8)

Guidance literature:

With cis-nitrous acid; Reduktion mit Zink oder Eisen +Salzsaeure und Oxidation in Gegenwart von Anilin mit Kaliumdichromat oder Braunstein_.;

Reference yield:

→ safranin O (477-73-6,74109-45-8)

Guidance literature:

With ethanol;

Reference yield:

2-methyl-p-phenylenediamine (95-70-5) → safranin O (477-73-6,74109-45-8)

Guidance literature:

Multi-step reaction with 2 steps

1: calcium chloride

2: alcohol

With ethanol; calcium chloride;

upstream raw materials:

N,N'-dichloro-2-methyl-cyclohexa-2,5-diene-1,4-diylidenediamine

4-methyl-N¹-phenylbenzene-1,3-diamine

o-toluidine

2-methyl-p-phenylenediamine

Downstream raw materials:

C₂₀H₁₉N₄

8-amino-3,7-dimethyl-10-phenyl-10H-phenazin-2-ylideneamine