2-(4-(N-hydroxycarbamimidoyl)phenyl)-N-hydroxybenzofuran-5-carboxamidine

Base Information

• Chemical Name: 2-(4-(N-hydroxycarbamimidoyl)phenyl)-N-hydroxybenzofuran-5-carboxamidine
• CAS No.: 854895-53-7
• Molecular Formula: C₁₆H₁₄N₄O₃
• Molecular Weight: 310.312
• Mol file: 854895-53-7.mol

Synonyms:2-(4-(N-hydroxycarbamimidoyl)phenyl)-N-hydroxybenzofuran-5-carboxamidine

Chemical Property of 2-(4-(N-hydroxycarbamimidoyl)phenyl)-N-hydroxybenzofuran-5-carboxamidine

Chemical Property:

Purity/Quality:

Safty Information:

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Technology Process of 2-(4-(N-hydroxycarbamimidoyl)phenyl)-N-hydroxybenzofuran-5-carboxamidine

There total 1 articles about 2-(4-(N-hydroxycarbamimidoyl)phenyl)-N-hydroxybenzofuran-5-carboxamidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

2-(4-Cyanphenyl)-1-benzofuran-5-carbonitril (28718-79-8) → 2-(4-(N-hydroxycarbamimidoyl)phenyl)-N-hydroxybenzofuran-5-carboxamidine (854895-53-7)

Guidance literature:

With hydroxylamine hydrochloride; potassium tert-butylate; In dimethyl sulfoxide; at 20 ℃; for 96h;

Reference yield: 22.0%

2-(4-(N-hydroxycarbamimidoyl)phenyl)-N-hydroxybenzofuran-5-carboxamidine (854895-53-7) + dimethyl sulfate (77-78-1) → 2-(4-(N-methoxycarbamimidoyl)phenyl)-N-methoxybenzofuran-5-carboxamidine (854895-54-8)

Guidance literature:

With sodium hydroxide; In water; dimethyl sulfoxide; at 0 - 20 ℃;

upstream raw materials:

2-(4-Cyanphenyl)-1-benzofuran-5-carbonitril

Downstream raw materials:

2-(4-(N-methoxycarbamimidoyl)phenyl)-N-methoxybenzofuran-5-carboxamidine