1-(2-Methoxyphenyl)piperazine hydrochloride

Base Information

Chemical Name:1-(2-Methoxyphenyl)piperazine hydrochloride
CAS No.:5464-78-8
Molecular Formula:C11H17ClN2O
Molecular Weight:228.722
Hs Code.:29335990
European Community (EC) Number:226-762-6
NSC Number:28709
UNII:3XQ74IHW73
DSSTox Substance ID:DTXSID5051440
Wikidata:Q27258188
ChEMBL ID:CHEMBL1256365
Mol file:5464-78-8.mol

Synonyms:1-(2-methoxyphenyl)piperazine;1-(2-methoxyphenyl)piperazine dihydrochloride;1-(2-methoxyphenyl)piperazine hydrochloride;1-(ortho-methoxyphenyl)piperazine;o-methoxyphenylpiperazine

Suppliers and Price of 1-(2-Methoxyphenyl)piperazine hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
1-(2-Methoxyphenyl)piperazine hydrochloride 97%
100g
$ 111.00

Matrix Scientific
1-(2-Methoxyphenyl)piperazine hydrochloride 95+%
100g
$ 116.00

Frontier Specialty Chemicals
1-(2-Methoxyphenyl)piperazine hydrochloride 99%
25g
$ 32.00

Crysdot
1-(2-Methoxyphenyl)piperazine hydrochloride 95+%
100g
$ 49.00

Crysdot
1-(2-Methoxyphenyl)piperazine hydrochloride 95+%
500g
$ 134.00

Chemenu
1-(2-Methoxyphenyl)piperazine hydrochloride 95%
500g
$ 138.00

Aronis compounds
1-(2-Methoxyphenyl)piperazine hydrochloride
20mg
$ 30.00

American Custom Chemicals Corporation
1-(2-METHOXYPHENYL)PIPERAZINE HYDROCHLORIDE 95.00%
1G
$ 716.10

Alichem
1-(2-Methoxyphenyl)piperazine hydrochloride
1000g
$ 240.92

Alfa Aesar
1-(2-Methoxyphenyl)piperazine hydrochloride 97%
100g
$ 76.80

Total 123 raw suppliers

Chemical Property of 1-(2-Methoxyphenyl)piperazine hydrochloride

Chemical Property:

Appearance/Colour:off-white solid
Vapor Pressure:5.68E-06mmHg at 25°C
Melting Point:217-219 °C(lit.)
Refractive Index:1,574-1,576
Boiling Point:379.9 °C at 760 mmHg
Flash Point:154 °C
PSA：24.50000
Density:1.057 g/cm³
LogP:2.30060
Storage Temp.:-20°C Freezer
Sensitive.:Hygroscopic
Solubility.:Soluble in DMSO and Methanol.
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:228.1029409
Heavy Atom Count:15
Complexity:169

Purity/Quality:

98% ^*data from raw suppliers

1-(2-Methoxyphenyl)piperazine hydrochloride 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36-28A

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=CC=C1N2CCNCC2.Cl
Uses 1-(2-Methoxyphenyl)piperazine hydrochloride is used as reference material for forensic laboratories. 1-(2-Methoxyphenyl)piperazine hydrochloride is used as reference material for forensic laboratories. It is used in chemical synthesis studies.

Technology Process of 1-(2-Methoxyphenyl)piperazine hydrochloride

There total 5 articles about 1-(2-Methoxyphenyl)piperazine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.08%

: 95520-98-2
tert-butyl 4-(2-methoxyphenyl)piperazine-1-carboxylate

: 5464-78-8
1-(2-methoxyphenyl)piperazine hydrochloride

Guidance literature:: With hydrogenchloride; In diethyl ether;

Reference yield: 74.0%

: 821-48-7
bis-(2-chloroethyl)amine hydrochloride

: 90-04-0
2-methoxy-phenylamine

: 5464-78-8
1-(2-methoxyphenyl)piperazine hydrochloride

Guidance literature:: With 2-(2-methoxyethoxy)ethyl alcohol; at 150 ℃; for 12h;
DOI:10.1016/j.bmc.2016.09.005

Reference yield:

: 578-57-4
2-bromoanisole

: 5464-78-8
1-(2-methoxyphenyl)piperazine hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: sodium t-butanolate / 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾ / toluene / 100 °C / Inert atmosphere

2: hydrogenchloride / diethyl ether / 2 h

With hydrogenchloride; sodium t-butanolate; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; In diethyl ether; toluene;